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Postdoctoral -Cardiac Regeneration (proteomics) (M/F)

Il y a 3 mois


Paris, Île-de-France Institut Curie Temps plein
About us

Institut Curie is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness.

The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient.

Mission

Laboratory

We are looking for a highly motivated and productive post-doctoral fellow to join our team "Mechanisms of Cardiac Regeneration" headed by Phong NGUYEN ), at Institut Curie, Paris, France. Our research interests focus on uncovering the factors and mechanisms that allow the zebrafish heart to naturally recover and regenerate from an injury.

The project

Our recent results have identified a number of genes that are critical for regeneration to continue. In this project, we will examine whether the identified genes and signaling pathways are also important at the protein level using mass spectrometry. Confirmed candidates will be further examined genetically using gain- and loss-of-function studies. This project will be supported by FRM (Foundation pour la Recherche Médicale) and Labex DEEP.

Profile

Training and Skills required:

We are looking for a postdoc in cardiac regeneration (proteomics based) candidate:

The candidate should hold a PhD in biology, cell biology, biochemistry or related areas.

Fresh PhD graduates or with up to 3 years of postdoctoral experience. Applicants are invited to indicate the specific level of experience in these subjects.

o Expertise in generating proteomic datasets using mass spectrometry. Highly desirable if they have experience in proximity labeling approaches such as BioID or TurboID

o Expertise in validating proteomic datasets using techniques such as co-immunoprecipitation and immuno staining

o Proficient in molecular biology skills such as cloning, PCR and western blot

o Proficient in analyzing proteomic datasets

o Desirable but not necessary: experience in working with primary tissue, animal work or zebrafish handling

Language skills: Fluency in English. French is a plus.

Abilities

Ability to work independently, organize and manage tasks and be willing to working in a team.

Ability to effectively communicate in the form of writing, oral presentations, supervising students

The candidate should be highly motivated, curious, and enthusiastic to work in a collaborative team.

All our opportunities are open to people with disabilities

Contract information

Type of contract: Fixed-term contract (COD)

Starting date: As soon as possible

Duration: 18 months (renewable contract up to 3 years)

Working time: full time

Remuneration: according to the current grids

Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position: Paris, 5eme

Reference: NA

Please send your CV, letter of motivation and 3 references

CVs to be processed on the go, therefore the position could be filled before the deadline for applications.

Publication date: 17/06/2024

Deadline for application: 31/08/2024

Institut Curie is an inclusive, equal opportunity employer

and is dedicated to the highest standards of research integrity.