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Postdoctoral M/F- Systems Biology of Cancer Group
Il y a 3 mois
Paris
Institut Curie Research CenterInstitut Curie is one of the largest European institutions for cancer research with strong and oldinterdisciplinary traditions.
It also includes a hospital specialized in cancer treatment, and therefore covers acontinuum of expertise from fundamental research to patient care.
It is located in the centre of Paris in a bothcultural and scientific rich environment. The institute hosts a large collection of tumor samples andstructured medical data.Laboratory
Our research aims at deciphering the molecular determinants of cancer and make this knowledge available to improve patient management.
It is based on high-dimensional and multi-level omics tumor profiles, and proceed by sophisticated machine learning approaches as well as biological network modelling.
At Institut Curie our situation is ideal to pursue these goals, since the choice of collaborations with biologists and clinicians, and the many technological core facilities of the institute offer many options to set up original and cutting-edge projects.
We are also involved in many national and international (mainly European) projects with other laboratories in Spain, Germany, Italy, Norway, Netherlands, USA or Japan.
We are conducting a large-scale study of a lung cancer patient cohort and integrating multimodal dataincluding multiomics (including spatial omics), pathomics, radiomics and other clinical data. Data for ~400
patients have already been collected.
The main objective is twofold:
build efficient predictors of treatment
response and shed light on the mechanisms of tumor progression. The study involves four groups at Institut
Nicolas Girard lab (lung oncologist). The first three group leaders also hold chairs (or will soon for IB) at Paris
We expect a candidate with a strong background in statistics, machine learning, computational systems, biology or physics. The successful candidate should have experience in high-throughput data analysis in biology.
Ideally, the candidate should be able to demonstrate some knowledge of basic biological mechanisms involved in cancer and have experience of collaboration with biologists for solving concrete biological problems.
He/she will have to:
understand the biological and clinical questions related to cell fate decision, tumor heterogeneity, interaction with microenvironment, drug response; define the most appropriate statistical and/or machine learning approaches and develop them; carry out the analyses and discuss the results with biologists or clinicians.
The candidate must have a good knowledge in multidimensional data analysis in biology, and be proficient in high-level languages like Python or R.
Familiarity and experience with existing systems biology methods and software would represent a strong advantage.Excellent communication skills and team spirit, and an ability to work in autonomy are essential. Fluent English both spoken and written is required.
Degree:
PhD level in computer science, machine learning, bioinformatics or systems biology
All our opportunities are open to people with disabilities
Type of contract :
Fixed-term contract.
Working time :
full time- number of days
Remuneration :
according to the current grids
Benefits :
Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance
Location of the position :
Paris
- Short periods of travel: International conferences
Institut Curie is an inclusive, equal opportunity employer
and is dedicated to the highest standards of research integrity. #J-18808-Ljbffr
