Head of Pharmacokinetics and Pharmacodynamics
il y a 3 semaines
Pierre Fabre est le 2ème laboratoire dermo-cosmétique mondial, le 2ème groupe pharmaceutique privé français et le leader des produits vendus hors prescription dans les pharmacies en France.
Son portefeuille compte plusieurs franchises médicales et marques internationales dont Pierre Fabre Oncologie, Pierre Fabre Dermatologie, Eau Thermale Avène, Klorane, Ducray, René Furterer, A-Derma, Naturactive et Pierre Fabre Oral Care.
Implanté depuis toujours en région Occitanie, fabricant plus de 95% de ses produits en France, le groupe emploie près de 10 000 collaborateurs dans le monde et distribue ses produits dans quelque 130 pays. Pierre Fabre est détenu à 86% par la Fondation Pierre Fabre, une fondation reconnue d’utilité publique, et secondairement par ses collaborateurs à travers un plan d’actionnariat salarié.
En 2021, Ecocert Environnement a évalué la démarche de responsabilité sociétale et environnementale du Groupe selon la norme ISO 26000 du développement durable et lui a attribué le niveau « Excellence ».
Pierre Fabre est reconnu comme l’un des « Meilleurs Employeurs du Monde 2021 » par Forbes. Notre groupe est classé dans le Top 6 de l’industrie cosmétique et dans le Top 7 de l’industrie pharmaceutique dans le monde. Nous sommes convaincus que notre engagement et notre passion font préserver notre indépendance et vivre notre raison d'être.
Votre missionWe are looking for a Pharmacokinetics/Pharmacodynamics Group Leader to lead a team of 6 professionals, including PKPD project leaders, Modeling and Simulation experts, and Clinical Pharmacology specialists. The team is responsible for early DMPK and PK/PD studies of both small and large molecules, as well as clinical pharmacology across all phases of clinical development. In this role, you will guide the group in strategy and functional expertise, establish a cohesive PBPK-based modeling approach, mentor your team, and oversee their training and development. You will also work closely with internal experts in data science, oncology, rare diseases, toxicology, and biomarkers to ensure a unified project strategy.
Key Responsibilities:- Lead, coach, and develop a team of experts in pharmacokinetics, pharmacodynamics, and clinical pharmacology.
- Provide expert guidance in developing comprehensive DMPK, PK/PD, and regulatory strategies from target validation through post-registration stages.
- Collaborate with internal stakeholders, including specialists in data science, oncology, rare diseases, toxicology, and biomarkers, to ensure alignment and coherence in project strategies.
- Oversee the group's activities and ensure the continuous professional growth and development of your team.
- Foster a culture of generosity, focusing on supporting and enabling the success of others, creating an environment where your team feels motivated to contribute their best.
- At least 10 years of experience in scientific research within the pharmaceutical industry, specifically in areas related to PK/PD/ADME science.
- Expertise in modeling and simulation approaches.
- Strong experience in either early-stage small molecule discovery or Clinical Pharmacology.
- Experience in leveraging ADME and PK/PD science to address efficacy and safety questions related to human exposure, and influence project strategies, advise on therapeutic dosing design and candidate selection, guide drug discovery strategy, and implement adequate de-risking plans.
- Demonstrated leadership skills, with experience managing teams and individuals.
- Strong expertise in regulatory submissions to health authorities.
- Experience in the fields of oncology and/or rare diseases.
- Advanced skills in data analysis and biomarker development.
Nous sommes convaincus que la diversité est une source d’épanouissement, d’équilibre social et de complémentarité pour nos collaborateurs, nos offres sont donc ouvertes à toutes et tous sans restriction.
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