Head of Pharmacokinetics and Pharmacodynamics

il y a 3 semaines


Toulouse, France Pierre Fabre Temps plein
Qui sommes-nous ?

Pierre Fabre est le 2ème laboratoire dermo-cosmétique mondial, le 2ème groupe pharmaceutique privé français et le leader des produits vendus hors prescription dans les pharmacies en France.

Son portefeuille compte plusieurs franchises médicales et marques internationales dont Pierre Fabre Oncologie, Pierre Fabre Dermatologie, Eau Thermale Avène, Klorane, Ducray, René Furterer, A-Derma, Naturactive et Pierre Fabre Oral Care.

Implanté depuis toujours en région Occitanie, fabricant plus de 95% de ses produits en France, le groupe emploie près de 10 000 collaborateurs dans le monde et distribue ses produits dans quelque 130 pays. Pierre Fabre est détenu à 86% par la Fondation Pierre Fabre, une fondation reconnue d’utilité publique, et secondairement par ses collaborateurs à travers un plan d’actionnariat salarié.

En 2021, Ecocert Environnement a évalué la démarche de responsabilité sociétale et environnementale du Groupe selon la norme ISO 26000 du développement durable et lui a attribué le niveau « Excellence ».

Pierre Fabre est reconnu comme l’un des « Meilleurs Employeurs du Monde 2021 » par Forbes. Notre groupe est classé dans le Top 6 de l’industrie cosmétique et dans le Top 7 de l’industrie pharmaceutique dans le monde. Nous sommes convaincus que notre engagement et notre passion font préserver notre indépendance et vivre notre raison d'être.

Votre mission

We are looking for a Pharmacokinetics/Pharmacodynamics Group Leader to lead a team of 6 professionals, including PKPD project leaders, Modeling and Simulation experts, and Clinical Pharmacology specialists. The team is responsible for early DMPK and PK/PD studies of both small and large molecules, as well as clinical pharmacology across all phases of clinical development. In this role, you will guide the group in strategy and functional expertise, establish a cohesive PBPK-based modeling approach, mentor your team, and oversee their training and development. You will also work closely with internal experts in data science, oncology, rare diseases, toxicology, and biomarkers to ensure a unified project strategy.

Key Responsibilities:
  • Lead, coach, and develop a team of experts in pharmacokinetics, pharmacodynamics, and clinical pharmacology.
  • Provide expert guidance in developing comprehensive DMPK, PK/PD, and regulatory strategies from target validation through post-registration stages.
  • Collaborate with internal stakeholders, including specialists in data science, oncology, rare diseases, toxicology, and biomarkers, to ensure alignment and coherence in project strategies.
  • Oversee the group's activities and ensure the continuous professional growth and development of your team.
  • Foster a culture of generosity, focusing on supporting and enabling the success of others, creating an environment where your team feels motivated to contribute their best.
Qui êtes-vous ? Required Qualifications:
  • At least 10 years of experience in scientific research within the pharmaceutical industry, specifically in areas related to PK/PD/ADME science.
  • Expertise in modeling and simulation approaches.
  • Strong experience in either early-stage small molecule discovery or Clinical Pharmacology.
  • Experience in leveraging ADME and PK/PD science to address efficacy and safety questions related to human exposure, and influence project strategies, advise on therapeutic dosing design and candidate selection, guide drug discovery strategy, and implement adequate de-risking plans.
  • Demonstrated leadership skills, with experience managing teams and individuals.
  • Strong expertise in regulatory submissions to health authorities.
Preferred Qualifications:
  • Experience in the fields of oncology and/or rare diseases.
  • Advanced skills in data analysis and biomarker development.

Nous sommes convaincus que la diversité est une source d’épanouissement, d’équilibre social et de complémentarité pour nos collaborateurs, nos offres sont donc ouvertes à toutes et tous sans restriction.

#J-18808-Ljbffr

  • Toulouse, France Pierre Fabre group Temps plein

    Head of Pharmacokinetics and Pharmacodynamics - M/F/D Locations: France - Toulouse - Langlade Time Type: Full time Posted on: Posted Today Job Requisition ID: JR107060 Who we are? Pierre Fabre is the 2nd largest dermo-cosmetics laboratory in the world, the 2nd largest private French pharmaceutical group and the market leader in France for products sold over...


  • Toulouse, France Pierre Fabre Temps plein

    Qui sommes-nous ? Pierre Fabre est le 2ème laboratoire dermo-cosmétique mondial, le 2ème groupe pharmaceutique privé français et le leader des produits vendus hors prescription dans les pharmacies en France. Son portefeuille compte plusieurs franchises médicales et marques internationales dont Pierre Fabre Oncologie, Pierre Fabre Dermatologie, Eau...

  • Head of Digital Systems

    il y a 4 semaines


    Toulouse, Occitanie, France Just Evotec Biologics EU Temps plein

    Job Title: Head of Digital SystemsAbout the Role:We are seeking a highly skilled and experienced Digital Systems Leader to join our team at Just Evotec Biologics EU. As the Head of Digital Systems, you will be responsible for leading the installation, configuration, deployment, start-up, validation, day-to-day operations, and lifecycle management of the full...


  • Toulouse, France Ascendance Flight Technologies Temps plein

    At Ascendance we are building tomorrow’s hybrid-electric aviation with ATEA, a unique Vertical Take-Off and Landing (VTOL) aircraft powered by STERNA, our in-house hybrid-electric propulsion system. We focus our efforts in designing an innovative, safe, silent, clean and affordable aircraft that will be able to blend into existing infrastructures and...

  • Head of Digital Systems

    il y a 4 semaines


    Toulouse, Occitanie, France Just Evotec Biologics EU Temps plein

    Unlock Your Digital PotentialJoin Just-Evotec Biologics EU as a Digital Leader and drive the transformation of our organization through cutting-edge digital systems and innovative technologies. As the Head of Digital Systems, you will be responsible for building and leading a high-performing Digital team, designing and implementing digital systems, and...


  • Toulouse, France Exotrail Temps plein

    **Job Description ‍** We are looking for a **Head of systems engineering **at our **Toulouse **site, to support the rapid growth of the spacevan activities within Exotrail. You will manage a tema of 10 systems engineers, working on our 3 ongoing projects in the in-orbit services team: development of spacevan LEO, spacevan GEO satellites, and R&D activity...

  • Head of Digital Systems

    Il y a 5 mois


    Toulouse, France Just Evotec Biologics EU Temps plein

    Head of Digital Systems (all genders) PERMANENT CONTRAT Toulouse, France Just-Evotec Biologics is seeking a Digital leader who will build the Digital team, culture and systems required to launch, sustain, and grow J.POD Toulouse as a world-class digitally-enabled platform for the development and manufacturing of advanced biopharmaceutical...


  • Toulouse, France Evotec Temps plein

    Vice President, Head of Manufacturing Operations - all genders The primary focus of this job is to lead and guide the late stage clinical and commercial biologics manufacturing operations (Cell Culture, Purification, and Support Services) at Just-Evotec Biologics’ state-of-the-art J.POD facility located in Toulouse, France. This position will partner with...

  • Head of Engineering

    il y a 4 semaines


    Toulouse, Occitanie, France L'ARCHE EN PAYS TOULOUSAIN Temps plein

    About the Role:As a Senior Software Developer, you will be responsible for designing, developing, and maintaining software applications to meet the needs of our customers. Your primary focus will be on writing clean, efficient, and well-documented code that meets the requirements of the project. Key Responsibilities:- Collaborate with cross-functional teams...


  • Toulouse, France Evotec Temps plein

    Vice President, Head of Manufacturing Operations - all genders The primary focus of this job is to lead and guide the late stage clinical and commercial biologics manufacturing operations (Cell Culture, Purification, and Support Services) at Just-Evotec Biologics’ state-of-the-art J.POD facility located in Toulouse, France. This position will partner with...


  • Toulouse, France Evote Temps plein

    Vice President, Head of Manufacturing Operations - all gendersThe primary focus of this job is to lead and guide the late stage clinical and commercial biologics manufacturing operations (Cell Culture, Purification, and Support Services) at Just-Evotec Biologics’ state of the art J.POD facility located in Toulouse, France. This position will partner with...


  • Toulouse, France Evote Temps plein

    Vice President, Head of Manufacturing Operations - all genders The primary focus of this job is to lead and guide the late stage clinical and commercial biologics manufacturing operations (Cell Culture, Purification, and Support Services) at Just-Evotec Biologics’ state of the art J.POD facility located in Toulouse, France. This position will partner with...

  • Head of infrastructure

    il y a 3 semaines


    Toulouse, France Urban Linker Temps plein

    DescriptionEn tant qu’Head of Infrastructure and Operations, vous serez en lien direct avec le CTO et vous intégrerez l’équipe technique passionnée par le Web3. Les responsabilités incluent :Manager, maintenir et évoluer l’infrastructure cloud de l’entreprise (avec forte implication sur Kubernetes).Développer et mettre en œuvre un plan...


  • Toulouse, France AIRBUS Temps plein

    Airbus recrute: **About us** ATR is the **world's number one aircraft manufacturer in regional aviation** providing a new generation of turboprops. We are a joint venture between **two European aeronautical heavyweights, Airbus and Leonardo.** From the world's largest cities, to our planet's most remote regions**, our purpose is to deliver air travel** to...


  • Toulouse, France Kicklox Temps plein

    L'offreProjet Head of IM SolutionsSecteurs AéronautiqueDescription de l'offreWe deliver outsized charter transport services to our client with 4 to 5 aircrafts, in view of generating new service revenues.To support our ramp-up, we are opening a Project Leader position, within the Engineering & Business Development team.Missions à réaliserCollect and study...


  • Toulouse, Haute-Garonne, France Brandinglo Temps plein

    Notre client, grand groupe industriel intervenant sur les secteurs Aéronautique & Spatial, recherche un Head of Business Development H/F.Malgré la crise, l’industrie aéronautique et spatiale fait face à des enjeux de taille qu’il est d’autant plus urgent de prendre en compte. Innovation, automatisation, maîtrise des coûts, écologie, font parti...


  • Toulouse, France Latecoere Temps plein

    **Date**:15 oct. 2024 **Localisation**: Toulouse Head Office, France **Entreprise**:LATECOERE Le titulaire du poste est chargé de diriger l’entité Customer Services de la branche Aerostructures, ainsi que de piloter son développement stratégique. Placé sous la responsabilité du Head of SPS (Special Products & Services), il est responsable de la...


  • Toulouse, France airbus Temps plein

    Job Description: About us ATR is the world's number one aircraft manufacturer in regional aviation providing a new generation of turboprops. We are a joint venture between two European aeronautical heavyweights, Airbus and Leonardo. From the world’s largest cities, to our planet’s most remote regions, our purpose is to deliver air travel to people,...


  • Toulouse, France IQVIA Temps plein

    We are currently recruiting for freelance registered pediatric nurses for France. As a freelance nurse you will **visit clinical trial patients in their homes **to carry out pharmacokinetics, taking vital signs, and supporting the infusion of medication to the patient. The workload can vary from week to week but can be planned in advance according to the...


  • Toulouse, France Airbus Group - Airbus Defence & Space Temps plein

    Stage - Support Head of Finance Satellites de Télécommunications et Navigations (H/F/D), ToulouseLieu(x)ToulouseStage - Support Head of Finance Satellites de Télécommunications et Navigations (H/F/D), ToulouseStage / Job d'étudiant / AlternanceAéronautiqueGestion comptabilité / FinanceIngénieurPubliée depuis 1 jourAirbus Group - Airbus Defence &...