Post-doctoral fellow in cellular biology research

il y a 4 semaines


Grenoble, Auvergne-Rhône-Alpes, France CEA Temps plein

Job context

Project purpose : The rise in diabetes cases worldwide has led to a pressing need to understand the underlying molecular mechanisms. In our lab, we are working on developing and characterizing human organ substitutes, organoids, and organoids-on-chip to address this challenge. Specifically, we aim to create a vascularized islet model to screen new therapeutic targets, drugs, and immunological approaches for type 1 diabetes.

Project description : Our project involves optimizing and developing a serpentine chip in collaboration with the CEA-Leti. Key objectives include the development of a pre-vascularized islet model, a permissive vascular microenvironment on-chip, analysis of vascular network development, and immunological approaches.

Candidate profile :

Required skills :

· Strong background in cell biology, particularly vascularization,

· Proficiency in image analysis and quantification (e.g., Imaris),

· Bioinformatics and transcriptomics analysis skills a plus,

· Excellent analytical and organizational skills,

· Ability to work independently and collaboratively as part of a team,

· Good communication skills.



  • Grenoble, Auvergne-Rhône-Alpes, France CEA Temps plein

    Research Position OverviewWe are seeking a highly motivated post-doctoral fellow to join our lab at CEA, focusing on the development of a vascularized islet model for type 1 diabetes research.Project ContextDiabetes is a major health concern worldwide, affecting millions of people. Our lab aims to understand the molecular mechanisms inducing type 1 diabetes...


  • Grenoble, Auvergne-Rhône-Alpes, France CEA Temps plein

    Job OpportunityWe are looking for a highly motivated post-doctoral researcher to join our team at CEA in the field of cell biology.The successful candidate will work on developing and characterizing human organ substitutes, organoids, and organoids-on-chip.Key ResponsibilitiesDevelop a pre-vascularized islet modelDesign a permissive vascular microenvironment...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Advanced Materials and Cellular Biology ResearcherThe ESRF's X-ray microscopy facility at the Nano-Imaging beamline ID16A is a world-leading research platform addressing research questions in advanced materials science, cellular biology, biomineralization, and neurosciences.You will develop an innovative research project in line with the beamline's...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Research OpportunityAt the European Synchrotron Radiation Facility (ESRF), we are seeking a highly motivated PhD researcher to join our Structural Biology Group. The successful candidate will pursue a project aimed at developing a new paradigm in macromolecular crystallography by focusing on room temperature data collection and embracing complementary...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Scientific OpportunityThe ID16A Nano-Imaging beamline at the European Synchrotron Radiation Facility (ESRF) offers a unique chance to develop innovative research projects in cellular biology, neurosciences, biomineralization, and advanced materials science. Our high-brilliance beam enables coherent imaging techniques, X-ray fluorescence microscopy, and...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Research OpportunityYou will develop advanced X-ray imaging workflows for the biological user community, focusing on high-resolution cryo tomography and correlative multi-modal investigations across length scales. This role requires collaboration with European research infrastructures to validate developments through applications in the field.RequirementsPhD...

  • Senior Research Fellow

    il y a 4 semaines


    Grenoble, Auvergne-Rhône-Alpes, France Embl-Ebi Temps plein

    Your RoleWe are seeking a highly motivated and innovative researcher to develop an independent research program in structural biology. The successful candidate will have a strong background in biological sciences and a proven track record of research excellence.The EMBL Grenoble Unit is a world-leading research institution, and this position offers a unique...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Research OpportunityThe ESRF is seeking a highly motivated PhD student to join our team and contribute to the development of novel methods for fragment screening in the era of Artificial Intelligence. The successful candidate will work on identifying compounds that modulate the activity of the exotoxin A protein from Pseudomonas aeruginosa using a...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Position OverviewThe ESRF is seeking a postdoctoral fellow to work on multiresolution X-ray CT and 4D X-ray CT at the imaging beamlines BM18 and BM05. The successful candidate will have a PhD in Geosciences, Geophysics, Materials Science, Engineering, or Physics, obtained less than 3 years ago.Key ResponsibilitiesDevelop in-house research projects and...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Geoscience Research OpportunitiesAbout 40% of the ESRF's beamlines are dedicated to Geosciences, utilizing the exceptional beam properties of the ESRF-EBS. We are seeking a postdoctoral fellow to work on multiresolution X-ray CT and 4D X-ray CT at the imaging beamlines BM18 and BM05.Research FocusPolar sea ice, volcanic lavas, and fluid flow through...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    About the PositionAt ESRF, we are seeking a talented PhD student to join our team and contribute to the research on Pseudomonas aeruginosa.The successful candidate will work under the supervision of our expert researchers to identify compounds that modulate the activity of the exotoxin A enzyme.This project combines AI-based virtual screening, activity...


  • Grenoble, Auvergne-Rhône-Alpes, France CEA Temps plein

    Research Opportunities at CEAWe are seeking a highly motivated and talented postdoctoral researcher to join our team at the French Alternative Energies and Atomic Energy Commission (CEA). Our research focuses on advancing the understanding of the complement system and its structural components, with a primary emphasis on autoimmune and chronic inflammatory...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Research Opportunities at ESRFESRF is seeking a highly motivated Postdoctoral Fellow to join our team at the High-Pressure Beamline. As a key member of our research group, you will participate in ongoing research programs, operate the beamline, and develop your own research program in collaboration with our team.About the BeamlineBeamline ID15B is a premier...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Job Description We are seeking a highly skilled Postdoctoral Fellow to join our team at the ESRF in Grenoble, France. As a key member of our research group, you will contribute to the running and development of the High-Pressure beamline, which is a premier X-ray powder and single crystal diffraction station dedicated to research at extreme pressures and...


  • Grenoble, Auvergne-Rhône-Alpes, France CEA Temps plein

    Job Offer Our research team at the CEA is committed to advancing the understanding of the complement system and its structural components. We are seeking a highly motivated and talented postdoctoral researcher to explore the antigenic determinants and the pathogenicity of the anti-C1q autoantibodies in systemic lupus erythematosus. Key Responsibilities: ...


  • Grenoble, Auvergne-Rhône-Alpes, France EMBL Temps plein

    Job SummaryWe are seeking a highly motivated Postdoctoral Organic/Medicinal Chemist to join our team at EMBL Grenoble. The successful candidate will contribute to the design, synthesis, and optimization of novel bioactive compounds.Key ResponsibilitiesDesign and synthesize new bioactive compounds for various target proteins/receptors in medicinal chemistry...


  • Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

    Research Opportunity in BiophysicsWe are seeking a highly motivated and skilled researcher to join our team at ESRF to investigate phase separating proteins.As a Research Scientist in Biophysics, you will work on a project that combines X-ray photon correlation spectroscopy (XPCS) and small angle X-ray scattering (SAXS) to study the structural and dynamic...

  • Senior Research Scientist

    il y a 3 semaines


    Grenoble, Auvergne-Rhône-Alpes, France EMBL Temps plein

    Research OpportunityEMBL Grenoble is seeking a talented individual to lead an independent and innovative integrated structural biology research programme.This position offers the opportunity to develop a cutting-edge research programme addressing important biological problems.Prospective avenues include incorporating synthetic biology technologies and...


  • Grenoble, Auvergne-Rhône-Alpes, France EMBL Temps plein

    Research OpportunitiesWe are seeking a highly motivated and ambitious researcher to lead an independent and innovative integrated structural biology research programme at EMBL Grenoble.The successful candidate will have a strong track record of developing original and impactful research programmes, and will be able to integrate into and take full advantage...


  • Grenoble, Auvergne-Rhône-Alpes, France CEA Temps plein

    Description of the PositionThis role is part of a research team at CEA focused on developing human organ substitutes, organoids, and organoids-on-chip. Specifically, the goal is to create a vascularized islet-model to understand type 1 diabetes mechanisms, enabling therapeutic target screening, drug development, and immunological approaches.Project...