Post Doctoral researcher
il y a 1 semaine
Postdoctoral Position at Vision Institute (Paris, France) in Retinal Pathology and Development of Next-Generation TreatmentsA two-year (one-year renewable) postdoc position funded by INSERM is available at the Institut de la Vision (IDV) for a highly motivated postdoctoral researcher to understand the molecular and cellular mechanisms underlying VEGF resistance in several eye diseases and evaluate next generation treatments.Most retinopathies, including diabetic retinopathies, involve extensive vascular remodeling marked by vascular leakage, edema, and pathological neovascularization that can rapidly impair vision if left untreated. Current therapy relies mainly on intravitreal anti-VEGF injections, which help many patients but show major limitations in the diabetic retinopathy patient population, where resistance can reach about 30%, leaving many without effective options. The mechanisms behind anti-VEGF resistance in these patients remain poorly understood, and a deeper understanding is essential for developing future treatments. Elevated inflammatory cytokines and integrins have been reported in multiple cancer and retinopathy studies, suggesting a role in resistance. This project will combine state-of-the-art quantification of adhesion molecules and inflammatory cytokines in ocular fluids from patients with in vitro and in vivo studies to identify molecules associated with VEGF resistance in diabetic retinopathy and to develop new models of VEGF-resistant retinopathies. Finally, the project will evaluate the therapeutic potential of a specific integrin inhibitor for treating VEGF-resistant retinopathies.The project will be conducted within the framework of an international collaboration between INSERM (IDV, Paris, France) and ICMR (Narayana Netralaya Foundation, Bengaluru, India). The position involves analyzing multi-omics data from existing human patient cohorts and developing models of VEGF resistant proliferative retinal diseases. Investigations of vascular remodeling will employ a broad range of in vitro and in vivo methodologies, including immunochemistry on retinal flatmounts, live imaging, bulk and single-cell RNA sequencing. The successful candidate will join the “Inflammation and Immunology in Retinal Diseases” team at IDV under the supervision of Dr. Guillonneau, a dynamic and multidisciplinary team with expertise spanning molecular to cellular mechanisms, and will also collaborate closely with the GROW research lab, led by Dr. Arkasubhra Ghosh.Candidates with a recent PhD in Neuroscience and experience with relevant experimental techniques (bioinformatics, RNAseq, multiplex ELISA, immunohistochemistry and animals models) are encouraged to apply. Candidates whose profiles partly overlaps the requirements but who have a strong interest in acquiring the other expertise are also encouraged to apply.The IDV is one of the leading European research centers focused on ocular diseases. It unites researchers, clinicians, and industry partners under one roof to advance the discovery, testing, and development of treatments and technological innovations that benefit visually impaired patients. Postdocs also benefit from professional development opportunities at both the IDV and Sorbonne University.To apply for the position, please send a motivation letter with a statement of research interest and a summary of previous research activity, a detailed curriculum vitae, and two reference letters to Xavier Guillonneau (xavier.guillonneau@inserm.fr).
-
Post Doctoral researcher
il y a 2 semaines
Greater Paris Metropolitan Region, France INSERM Temps pleinPostdoctoral Position at Vision Institute (Paris, France) in Retinal Pathology and Development of Next-Generation TreatmentsA two-year (one-year renewable) postdoc position funded by INSERM is available at the Institut de la Vision (IDV) for a highly motivated postdoctoral researcher to understand the molecular and cellular mechanisms underlying VEGF...
-
Post-doctoral Researcher, Cognitive Science and
il y a 2 semaines
Paris, France Meta Temps plein**Post-doctoral Researcher, Cognitive Science and Machine learning (PhD Grad) Responsibilities**: - Collaborate on research to advance the science and technology of intelligent machines - Devise better data-driven models of human behavior - Influence progress of relevant research communities by producing publications - Collaborate and increase productivity...
-
Post Doctoral researcher
il y a 1 semaine
Paris, France Inserm Temps pleinPostdoctoral Position at Vision Institute (Paris, France) in Retinal Pathology and Development of Next-Generation TreatmentsA two-year (one-year renewable) postdoc position funded by INSERM is available at the Institut de la Vision (IDV) for a highly motivated postdoctoral researcher to understand the molecular and cellular mechanisms underlying VEGF...
-
Post-doctoral researcher Healthy Teeth
il y a 5 jours
Paris, Île-de-France Junia Temps pleinDepuis 1885, JUNIA, affiliée à l'Université Catholique de Lille, forme des ingénieurs prêts à relever les grandes transitions et les défis de demain. Grâce à ses programmes emblématiques HEI, ISA et ISEN, JUNIA développe une expertise pluridisciplinaire couvrant l'industrie, le numérique, l'agroalimentaire, les agricultures, la santé et...
-
Senior Research Fellow — Policy Research
il y a 3 jours
Paris, France European Institute of Policy Research and Human Rights SIA Temps pleinA prestigious research institute in Paris is inviting applications for the Senior Research Fellowship. This role is open to candidates enrolled in or holding a Master's or Doctoral degree from any discipline. You will engage in groundbreaking research, collaborate with experts, produce publishable papers, and contribute to academic discussions. This...
-
Greater Paris Metropolitan Region, France Floware Temps pleinParis area | Doctoral research | Design | ️ Full-time | Bilingual EN/FR requiredFloware is a deeptech company disrupting how mobility data is produced, analyzed, and transformed into actionable insights. We combine edge IoT, data fusion, and AI to simplify mobility strategy for public and private actors.We are opening a CIFRE PhD position (funded doctoral...
-
Researcher-Junior(JRFP)
il y a 7 jours
Paris, France European Institute of Policy Research and Human Rights SIA Temps pleinThe European Institute of Policy Research and Human Rights is a prestigious institution that offers cutting-edge online programs designed to educate future leaders in policy research, human rights, and related disciplines. Our mission is to deliver world-class skill enhancing programs to candidates globally, equipping them with the knowledge and skills to...
-
Policy Researcher-Senior
il y a 3 jours
Paris, France European Institute of Policy Research and Human Rights SIA Temps pleinThe European Institute of Policy Research and Human Rights is a prestigious institution that offers cutting‑edge online programs designed to educate future leaders in policy research, human rights and related disciplines. Our mission is to deliver world‑class skill‑enhancing programs to candidates globally, equipping them with the knowledge and skills...
-
Senior Policy Research Fellow
il y a 3 jours
Paris, France European Institute of Policy Research and Human Rights SIA Temps pleinA leading research institution based in France invites applications for a Senior Research Fellowship. This role develops groundbreaking research on policy issues, with mentorship provided. Applicants should be enrolled in or have completed a Masters or Doctoral program. Open to diverse fields including Law, Engineering, and Social Sciences. The fellowship...
-
Research Fellow Jr.
il y a 4 jours
Paris, Île-de-France European Institute of Policy Research and Human Rights SIA Temps pleinThe European Institute of Policy Research and Human Rights is a prestigious institution that offers cutting-edge online programs designed to educate future leaders in policy research, human rights, and related disciplines. Our mission is to deliver world-class skill enhancing programs to candidates globally, equipping them with the knowledge and skills to...
