Researcher in Neuro-oncology and Immunology

il y a 4 semaines


Bordeaux, France CNRS Temps plein

Cette offre est disponible dans les langues suivantes:

- Français
- Anglais

Date Limite Candidature : jeudi 19 décembre 2024 23:59:00 heure de Paris

**Informations générales**:
**Intitulé de l'offre **:Chercheur en neuro-oncologie et immunologie H/F**
Référence : UMR5095-KILAUD-038
Nombre de Postes : 1
Lieu de travail : BORDEAUX
Date de publication : jeudi 28 novembre 2024
Type de contrat : Chercheur en contrat CDD
Durée du contrat : 12 mois
Date d'embauche prévue : 1 mars 2025
Quotité de travail : Complet
Rémunération : entre 2 991,58 euros et 3 477,33 euros bruts mensuels selon expérience
Niveau d'études souhaité : Doctorat
Expérience souhaitée : Indifférent
Section(s) CN : 22 - Biologie cellulaire, développement, évolution-développement, reproduction

**Missions**:
**Activités**:

- Activités principales
- Des injections de métabolites marqués en C13 seront réalisées in vitro dans les macrophages ou les cellules microgliales.
- Analyses en immunofluorescence et histologie. Les nouveaux marqueurs détectés dans les premières expériences seront supprimés par l'utilisation de la technique Crispr-Cas9 sur les cellules de glioblastome.

Activités secondaires
- Participer aux activités collectives du laboratoire (réunions du groupe, séminaires, présentations des résultats, etc.)
- Interagir avec les autres membres de l'équipe et/ou de l'Unité de recherche, avec les collaborateurs.

**Compétences**:

- Compétences principales:

- Solide formation en cytométrie en flux et culture de cellules type macrophages ou microglie.
- Connaissances en immunologie et neuro-oncologie.
- Expérimentation animale requise de niveau 1 (manipulation de la souris, gavage, chirurgie).
- Des connaissances concernant le fonctionnement des systèmes métaboliques cérébraux ou du glioblastome seront appréciées.
- Compétences linguistiques : anglais lu parlé indispensable dans le groupe international.

Savoir-faire:

- Bonne maîtrise des techniques de cytométrie, de culture de cellules humaines, de microscopie, bonnes connaissances des flux métaboliques, analyses métabolomiques et transcriptomiques.
- S'adapter rapidement aux nouvelles méthodologies.
- Savoir utiliser les outils informatiques et les logiciels dédiés au traitement des données.

Savoir-être:

- Le ou la postdoctorante devra être motivé-e, rigoureux-se, doté-e d'un bon sens de l'organisation et capable d'autonomie.

**Contexte de travail**:
Le ou la post-doctorante travaillera dans le cadre de l'obtention d'un financement compétitif obtenu auprès de l'INCA, avec l'appel d'offres PLBIO 2022. Ce consortium scientifique de laboratoires très performants comprend des équipes basées exclusivement sur l'Université de Bordeaux (CNRS, INSERM). Le groupe de Thomas Daubon, nouveau dans la structure IBGC UMR5095, regroupe une Maitre de Conférences, 2 postdoctorants, 5 doctorants, des étudiants en master, 2 ingénieures d’étude.
Thomas Daubon a de nombreuses collaborations locales, nationales, mais aussi internationales, qui seront autant d'atouts pour la réussite de ce projet.
Ce contrat est de 12 mois et pourra être prolongé au moins d’un an.



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