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Post-doc Position in Fibrosis Research
il y a 1 semaine
A post-doctoral contract funded by BPI France is available in the BC2M (Biocommunication in Cardio-Metabolics) laboratory in the Faculty of Pharmaceutical Sciences at the University of Montpellier (France). Our laboratory is interested in biocommunication between the cardiovascular/renal axis and metabolic tissues in metabolic syndrome. Our work focuses on a better understanding of the mechanisms involved in the damage caused to target tissues during metabolic dysfunction, and on the biocommunication pathways between these tissues. The team has recently obtained, along with 2 industrial R&D partners (RD Néphrologie and Phost'in Therapeutics) a regional I-Démo funding to develop the GLYCO2FIB project focusing on fibrosis.
**Site web**:
**Poste et missions**:
Fibrosis is a chronic condition in which functional tissue is replaced by a rigid, disorganised extracellular matrix, leading to impaired tissue function and, consequently, organ failure. Chronic renal failure, heart failure and non-alcoholic steatohepatitis (NASH) are among the most common fibrotic disorders. These chronic diseases are diagnosed at a late stage, when the organs have suffered significant damage, therefore the means of halting their progression are limited, which represents a major public health challenge.
In this context, the aim of the project is to (i) advance our understanding of the common mechanisms underlying fibrotic pathologies, in order to (ii) advance the development of innovative therapies, in particular via two innovative therapeutic approaches developed in Occitanie by the partners of the funded project.
The work will involve fibrosis models using cultured cells as well as rodent models of fibrosis diseases.
**Mobilité géographique**:
- Pas de déplacement**Télétravail**:
- Impossible**Prise de fonction**:
- 30/04/2024**Profil**:
Competences and experience are required in cellular and molecular biology, biochemistry, animal experimentation, cell culture, immunostaining, knowledge in metabolic diseases.
The language used in the lab can be french or english.
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