Senior Scientist

Senior Scientist – Orakl Oncology Join to apply for the Senior Scientist role at Orakl Oncology At Orakl Oncology, we are accelerating the development of oncology treatments. Fewer than 5% of new cancer drugs succeed in clinical trials, so new methods are needed. We combine cutting‑edge biology and AI to build the next generation of insight platforms with the world’s largest cohort of patient tumor avatars. These avatars fuel our AI‑powered predictive engine, helping anticipate clinical trial outcomes, validate therapies, and uncover new drug candidates. Our mission is simple yet ambitious: to bring more effective treatments to patients who need them, and to make drug development smarter, faster, and more personalized. We collaborate with top hospitals, research institutes, and pharmaceutical companies worldwide. Backed by leading investors, we are a fast‑growing, mission‑driven startup at the intersection of science and technology. We are looking for a passionate and dynamic scientist to build the tools that will fuel Orakl’s drug development efforts. Your role will be to design, build and optimize new screening methods around organoid culture. You will drive high‑impact discovery efforts by designing and managing the execution of critical in‑house experiments, establishing external collaborations with key vendors, and ensuring high‑quality data generation. Requirements PhD in molecular biology, cancer biology, biotechnology, or related field; ~1–5 years postdoctoral or industry experience a plus. Strong, hands‑on expertise in 3D cell culture and patient‑derived organoids. Prior experience in drug screening, preferably high‑throughput screening. Proven proficiency with CRISPR gene editing in mammalian systems (ideally organoids): gRNA design, engineering, optimization, troubleshooting. Exceptional wet‑lab fundamentals: sterile technique, routine culture, molecular biology, cloning, assay development, QC. Demonstrated ability to independently plan, prioritize, and execute complex experimental pipelines with high quality and reproducibility. Strong analytical, quantitative data interpretation, and clear documentation/reporting skills. Nice to have Direct background in oncology research. Experience with pooled/arrayed CRISPR screens or other functional genomics approaches. Experience with drug‑response profiling in organoids (dose–response, time‑course, combination assays). Previous responsibility for managing CROs or academic collaborations. Experience mentoring junior scientists, lab technicians, and/or establishing lab standards. Prior involvement in early‑stage drug discovery or cross‑functional oncology research. Interview Process HR Call (15 minutes) – An initial discussion to better understand your background, experiences, and motivations. Technical Interview (45 minutes) – A deep dive into your technical skills and expertise relevant to the role. Engineering Case (60‑minutes presentation + discussion) – You will present a piece of work you have previously worked on and are proud of. This will be in front of the relevant members of the Orakl Oncology team; it can be done in person if possible. Founder Interview – As the final step of our recruitment process, you will meet the founders of Orakl Oncology in person at our office. This meeting is an opportunity for the founders to assess cultural fit and ensure alignment with our company values. Seniority level Mid‑Senior level Employment type Full‑time Job function Other Industries IT Services and IT Consulting #J-18808-Ljbffr