Head of Pharmacokinetics and Pharmacodynamics M/F/D

il y a 3 jours

Toulouse, France Pierre Fabre Laboratories Temps plein

Overview We are looking for a Pharmacokinetics/Pharmacodynamics Group Leader to lead a team of 6 professionals, including PKPD project leaders, Modeling and Simulation experts, and Clinical Pharmacology specialists, at Pierre Fabre Laboratories. The team is responsible for early DMPK and PK/PD studies of both small and large molecules, as well as clinical pharmacology across all phases of clinical development. In this role, you will guide the group in strategy and functional expertise, establish a cohesive PBPK-based modeling approach, mentor your team, and oversee their training and development. You will also work closely with internal experts in data science, oncology, rare diseases, toxicology, and biomarkers to ensure a unified project strategy. Key Responsibilities Lead, coach, and develop a team of experts in pharmacokinetics, pharmacodynamics, and clinical pharmacology. Provide expert guidance in developing comprehensive DMPK, PK/PD, and regulatory strategies from target validation through post-registration stages. Collaborate with internal stakeholders, including specialists in data science, oncology, rare diseases, toxicology, and biomarkers, to ensure alignment and coherence in project strategies. Oversee the group\'s activities and ensure the continuous professional growth and development of your team. Foster a culture of generosity, focusing on supporting and enabling the success of others, creating an environment where your team feels motivated to contribute their best. Required Qualifications At least 10 years of experience in scientific research within the pharmaceutical industry, specifically in areas related to PK/PD/ADME science. Expertise in modeling and simulation approaches. Strong experience in either early-stage small molecule discovery or Clinical Pharmacology. Experience in leveraging ADME and PK/PD science to address efficacy and safety questions related to human exposure, and influence project strategies, advise on therapeutic dosing design and candidate selection, guide drug discovery strategy, and implement adequate de-risking plans. Demonstrated leadership skills, with experience managing teams and individuals. Strong expertise in regulatory submissions to health authorities. Preferred Qualifications Experience in the fields of oncology and/or rare diseases. Advanced skills in data analysis and biomarker development. Details Seniority level: Director Employment type: Full-time Job function: Research Industries: Pharmaceutical Manufacturing #J-18808-Ljbffr

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