2018/10/02- Post-doctoral position: MR-Guided Focused Ultrasound in experimental model
il y a 4 jours
Type de structure : The Institut du Cerveau et de la Moelle épinière – ICM (Brain & Spine Institute) – is an international brain and spinal cord research center whose innovative concept and structure make it the only institute of its kind in the world. The ICM brings patients, doctors and researchers together with the aim of rapidly develop treatments for disorders of the nervous system and enable patients to benefit from them as quickly as possible.The Langevin Institute is a research unit affiliated with ESPCI Paris and CNRS. The researches conducted at the Institute aim at developing at he best world-level the physics of waves bringing together high level fundamental research, applied research, and company start ups in a thoroughly cross-disciplinary way.Contexte et mission : A full-time18-month postdoctoral position is available at the Center for Neuroimaging Research (CENIR) at ICM (Paris) in collaboration with the Institut Langevin (Paris) and the Neurodegenerative Diseases Research Group (Barcelona, Spain) to work on a new project recently funded by the Agence Nationale pour la Recherche (ANR) untitled “Focused ultrasound modulation of neuromelanin (NM) accumulation in a humanized murine model of Parkinson’s disease (PD)”. The goal of the project is to evaluate whether transcranial focused ultrasound (tFUS), an emerging non-invasive technology, can lower NM levels below their pathogenic threshold in NM-producing PD experimental models and prevent, halt or delay neuronal dysfunction and degeneration. If successful, this proposal will lay the groundwork for the development of a novel disease-modifying therapy for PD based on the modulation of NM levels with tFUS. CENIR is the ICM’s neuroimaging platform directed by Pr. Stéphane Lehéricy. This imaging facility consists primarily of human MRI scanners (3T), a small animal MRI scanner (Bruker Biospec 117/16 USR) equipped with an Image Guided Therapy (IGT) ultrasound system, and MEG, EEG, TMS and PET/MRI systems to study brain structure and function in normal and pathological conditions. Institut Langevin is expert in focused ultrasound technology (Drs. Jean-Francois Aubry and Michael Tanter).The overall project will involve transversal collaborations between experts in PD, experimental models, MRI and ultrasounds, cellular imaging and histology within and outside the Institute. Pr. Miquel Vila is the principal investigator at the Neurodegenerative Diseases Research Group (Barcelona, Spain) and has developed the NM-producing PD experimental models.The post-doctoral fellow will be involved in methodological developments of this new approach to trigger and enhance NM clearance. In this framework, the candidate will oversee the acquisition and analysis of data at 11.7T in murine model of Parkinson’s disease. He/She might also be involved in behavioral and histological studies.Recruitment starting date: October 2018Diplômes requis : The ideal candidate will have a PhD in medical imaging physics, ultrasound, MRI, biomedical engineering, neuroimaging, or related fields. She/he should have previously worked with murine models and have experience in ultrasound and/or MRI.Compétences requises : Animal handling. Good programming skills (Matlab, Python, C…). will be a plus. Good oral and writing skills in English and the ability to work independently and in collaboration are expected.Contact : Send CV and motivation letter to: mathieu.santin@icm-institute.org and jean-francois.aubry@espci.fr #J-18808-Ljbffr
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Paris, France France Life Imaging Temps pleinJob Title: Post-doctoral position in pre-clinical ultrasound and optical imaging, ParisCompany Description: The small animal imaging facility of Institut Cochin performs studies in ultrasound and bioluminescence imaging for both academic teams and private companies. It is specialized in in vivo evaluation and characterization of pathologies and runs 2 high...
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Post-doctoral Position in Ultrasound Imaging
il y a 4 jours
Paris, France France Life Imaging Temps pleinType de structure : Skills needed and information: The successful candidate will hold a Ph.D and will be mostly in charge to build and implement new US sequences on an ultraportable ultrafast US device. These new US sequences should be implemented to speed-up the acquisition rate and to optimize the setup sensibility and efficiency. Then implementation of...
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Paris, France France Life Imaging Temps pleinAperçu Type de structure : A postdoctoral position in multiparametric hepatic MRI is currently available at the Laboratory of Imaging Biomarkers in the Center of Research on Inflammation UMR 1149 INSERM - University Paris Diderot. The Center for Research on Inflammation Research, Inserm unit UMR1149, was created in 2014 and is distributed on the Bichat and...
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Paris, France France Life Imaging Temps pleinType de structure : Laboratory of Imaging Biomarkers of the Center of Research on Inflammation UMR 1149 INSERM -University Paris Diderot.Contexte et mission : The position involves the development, implementation and validation of MR acquisition and post-processing methods to obtain imaging biomarkers of chronic diseases and tumors in the liver and pancreas....
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POSTDOCTORAL RESEARCHER IN MR IMAGING OF PANCREATIC CANCER
il y a 4 jours
Paris, France European Society for Magnetic Resonance in Medicine and Biology Temps pleinPOSTDOCTORAL RESEARCHER IN MR IMAGING OF PANCREATIC CANCERPostdoctoral Researcher in MR Imaging of Pancreatic CancerTime-resolved diffusion and MRE for pancreatic cancer stratification and treatment response predictionJob type: PostdocJob location: ParisDeadline: 2025-02-30General information:Workplace: Center for Research on Inflammation, Inserm UMR...
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Post-doctoral Position in Immunology and Cancer
il y a 1 semaine
Paris, France Laboratoire d'immunologie et de Cancerologie integrative LICI -INSERM Temps plein**Site web**: **Poste et missions**: A post-doctoral position is available for working within the frame of a cancer immunology and immunotherapy projects using system biology approaches. Applicants will have a strong background in the field of immunology. The applicant should have good knowledge of biology, particularly in the field of cancer. A previous...
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Post-doctoral fellowship in MRI
il y a 4 jours
Paris, France France Life Imaging Temps pleinOverview Type de structure : Background Nonalcoholic steatohepatitis (NASH) represents an increasing health burden and is quickly becoming the main cause of liver cancer. Magnetic resonance imaging (MRI) proposes several attractive markers for the diagnosis of NASH. MR elastography, because of its sensitivity to tissue visco-elasticity, is a valuable tool...
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Postdoc: MR-Guided Ultrasound in Murine PD Model
il y a 4 jours
Paris, France France Life Imaging Temps pleinUn institut de recherche innovant à Paris propose un poste postdoctoral de 18 mois au sein du Centre de recherche en neuroimagerie. Le projet, financé par l'ANR, explore l'utilisation de l'ultrason transcrânien pour moduler les niveaux de neuromélanine dans un modèle de la maladie de Parkinson. Le candidat idéal doit avoir un doctorat en imagerie...
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Paris, France France Life Imaging Temps pleinOverviewType de structure : A postdoctoral position in radiomics of liver diseases is currently available at the Laboratory of Imaging Biomarkers of the Center of Research on Inflammation UMR 1149 INSERM - University Paris Diderot. The Center for Research on Inflammation Research, Inserm unit UMR1149, was created in 2014 and is distributed on the Bichat and...
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Paris, France Inria Temps pleinLe descriptif de l’offre ci-dessous est en Anglais_ **Niveau de diplôme exigé**: Thèse ou équivalent **Fonction**: Chercheur contractuel **Principales activités**: Post-doctoral position: "Computing transition rates: models and algorithms" Keywords: molecular dynamics, machine learning, rare event sampling Duration: 12 months, renewable up to 18...
