Molecular Biologist

il y a 3 semaines


Paris, Île-de-France Institut Curie Temps plein
Job Opportunity at Institut Curie

Institut Curie is a leading research center in the fight against cancer, with a strong international presence and a team of over 1000 employees. We are seeking a highly skilled engineer to join our Molecular Mechanism of Chromosome Dynamics group, led by Daniele Fachinetti.

Project Overview

The selected candidate will investigate the causes and consequences of centromere aberrations in cancer using interdisciplinary approaches in cell and cancer cell models. The goal is to elucidate the repair mechanisms acting at broken centromeres and develop novel imaging approaches to detect chromosome translocations.

Responsibilities
  • Cell culture, clone isolation, and characterization
  • Genome editing with CRISPR/Cas9 technology and lentivirus approaches
  • Microscopy techniques, including live cell imaging, super resolution, and multicolor FISH for karyotype analysis
  • Implementation of digital droplet PCR for measuring repetitive elements
  • Development of expansion microscopy on metaphase chromosomes
  • Molecular biology assays, including DNA, RNA, and protein extraction and cloning
  • Data analysis
  • Communication of results at meetings
Requirements

Candidates must hold an engineering degree or a master's degree in biology. Previous expertise in microscopy, tissue culture models, and molecular biology is recommended. A professional English level is required.

Contract Information

Type of contract: Fixed-term contract

Starting date: From July/September

Duration: 18 months renewable

Working time: Full-time

Remuneration: According to the current grids

Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance

Location of the position: Paris 5th (downtown)


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