Postdoctoral Researcher in FGFR3-Related Disorders and Aging
il y a 4 semaines
The Imagine Institute is a cutting-edge research structure located within Necker Children's Hospital in Paris. Our research labs focus on understanding the molecular mechanisms of genetic diseases affecting the immune system, skeletal dysplasia, nervous system, stem cell differentiation, kidney physiology, and metabolism.
We offer a unique environment where clinical and basic science synergize to produce groundbreaking contributions in areas like osteochondrodysplasia, immunology, molecular genetics, cell biology, and clinical and translational research.
MissionA postdoctoral position is available in the laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia, led by Dr. Laurence Legeai-Mallet, to investigate the impact of FGFR3 signaling alterations on bone functions and premature aging.
The laboratory studies rare skeletal disorders affecting bone and/or cartilage formation from early embryonic development until adulthood. We are conducting pre-clinical studies to test and identify drugs able to correct long bone growth plate, craniofacial, and spine anomalies in FGFR3-related animal models.
Our project aims to define the cellular and molecular regulatory pathways involved in these effects, decipher the complexity of multi-systemic impairments in FGFR3-associated disorders, and develop novel therapeutic approaches for adult FGFR3-related patients and premature bone aging.
We are seeking a postdoctoral researcher with solid experience in molecular and cell biology, and in mouse model. The candidate must have a PhD in a relevant field, be self-motivated, organized, creative, able to work independently, lead the project, optimize and/or develop new study systems, communicate effectively with the team and external collaborators, and be fluent in English.
The position is offered for two years with a salary depending on experience. Please send a concise cover letter with a summary of previous and current research activity, detailed curriculum vitae, and the contact information for two references.
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Postdoctoral Researcher in FGFR3-related Disorders and Aging
il y a 1 semaine
Paris, Île-de-France Imagine - Institut des maladies génétiques Temps pleinAbout the PositionThe Imagine Institute is seeking a highly motivated Postdoctoral Researcher to join its research team. The successful candidate will work under the supervision of Dr. Laurence Legeai-Mallet to investigate the impact of FGFR3 signaling alterations on bone functions and premature aging.The research focuses on rare skeletal disorders affecting...
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Postdoctoral Researcher in FGFR3-Related Disorders and Aging
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Paris, Île-de-France Imagine - Institut des maladies génétiques Temps pleinAbout the PositionThe Imagine Institute is a research structure located within Necker Children's Hospital (Paris). Our research labs are focused on understanding the molecular mechanisms of genetic diseases that affect the adaptive and innate immune systems, the skeletal dysplasia, the nervous system, stem cell differentiation, kidney physiology, metabolism,...
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