Molecular Biology Research Engineer
il y a 3 jours
The Molecular Mechanism of Chromosome Dynamics group at Institut Curie is seeking a highly skilled engineer to contribute to the development of basic research and innovation in cancer diagnosis, prognosis, and therapeutics.
The selected candidate will study the causes and consequences of centromere aberrations in cancer using interdisciplinary approaches in cell and cancer cell models.
The engineer will work together with members of the Fachinetti group to elucidate the repair mechanisms acting at broken centromeres and develop novel imaging approaches to detect chromosome translocations.
The key responsibilities of the position include:
- Cell culture, clone isolation and characterization, treatment with various compounds;
- Genome editing with CRISPR/Cas9 technology and lentivirus approaches;
- Microscopy techniques (live cell imaging, super resolution, multicolor FISH for karyotype analysis);
- Implementation of the digital droplet PCR for measuring repetitive elements;
- Development of expansion microscopy on metaphase chromosomes;
- Molecular biology assays (DNA, RNA and protein extraction-Implementing, cloning);
- Data analysis;
- Communication of results at meetings.
The ideal candidate will hold an engineering degree or a master's degree in biology and have previous expertise in microscopy, tissue culture models, and molecular biology. A professional English level is required.
Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity.
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il y a 3 semaines
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il y a 1 mois
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il y a 11 heures
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il y a 2 jours
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