Quantum Electrochemistry Detection of DNA-Protein Interactions for Cancer Screening Specialist
il y a 4 semaines
Our research group at IEMN Lille is seeking a highly skilled researcher to join our team in the development of innovative lab-on-chip devices for detecting circulating tumor cells and extracellular vesicles with high efficiency. The successful candidate will work closely with our experimental groups, including the group in LIMMS/IIS Tokyo (Japan), to advance the molecular-scale understanding of DNA-protein interactions and improve the modeling of electron quantum transport.
Key Responsibilities:- Conduct extensive all-atom molecular simulations to characterize DNA aptamers, their bonding with electrodes and redox molecules, and their dynamical fluctuation trajectory in solution.
- Develop quantum-mechanical electron transport simulations to calculate the tunneling current as a function of the DNA-protein interaction, to be compared with experiments.
- Collaborate with experimental groups to design and optimize lab-on-chip devices for detecting CTCs and EVs.
- PhD in Applied Mathematics, Computational Modeling, Fundamental Physics, Biophysics, Statistical Mechanics, Molecular Modeling, or Basic Cell Biology.
- Working knowledge of Linux/Unix, C/C++/Fortran, and Python.
- Strong background in at least three of the following areas: applied mathematics, computational modeling, fundamental physics, biophysics, statistical mechanics, molecular modeling, basic cell biology, bioinformatics.
- Fully-funded GRAEL grant from University of Lille.
- Opportunity to work with a highly skilled research team and contribute to cutting-edge research in quantum electrochemistry and DNA-protein interactions.
- Collaboration with international research groups, including the group in LIMMS/IIS Tokyo (Japan).
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