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Apprentice in Biochemistry/Proteomic - Apprenti(e) en Biochimie/proteomique (H/F)
General Summary:
In collaboration with MS team and biochemistry team you will participate to the development of new probes allowing the binding site identification of a target of interest. Different approaches of biochemistry will be first applied, after different steps of validation, the assay will be done with a MS read-out to determine the peptide sequence and the amino acid where the binding occurs
Missions and responsibilities:
- Collect, understand and summarize a publication- Contribute to proteomic studies to identify the binding site of a known target from a recombinant model and in a cell model.- Identify and implement novel approaches in biochemistry compatible with proteomic analysis based on data from the literature, in collaboration with the tutor.- Interpret and exploit experimental results in the biological context in coordination with proteomics, bioinformatics teams.- Participate in the development and implementation of new methodologies and strategies applied to sample preparation for proteomics.- Communicate effectively internally through written and oral communication and presentations.- Demonstrate excellent organization/multitasking, communication and analytical skills with ability to effectively present scientific findings to project team- Demonstrate strong problem-solving capabilities.- Closely collaborate with other proteomic team
Knowledge, skills and abilities:
- Excellent communication and interpersonal skills- Knowledge in cell culture using cell lines, primary cells, bacteria, or yeast.- Knowledge in proteomics sample preparation for mass spectrometry analysis.- Knowledge with SDS-PAGE and Western blotting.- Scientific rigor and excellent analytical capabilities.- Capability to work with interdisciplinary teams.
Experience and education:
- Master/ingenior student with a background in chemistry and proteomics
Duration: ~1 year
