Postdoctoral Position in Organic/bioconjugation Chemistry

il y a 2 jours

Dijon, France Université Bourgogne Europe - ICMUB Lab - SATT Sayens Temps plein

**About the Lab**
- We are offering an 18-month postdoctoral position in organic / bioconjugation chemistry within the RITM team (Radiopharmaceuticals, Imaging, Therapy, and Multimodality), as part of a technology maturation project funded by SATT Sayens.

**Scientific Context**
- Due to its high efficiency and selectivity, the labeling can be performed directly in vivo, once the vector has accumulated in the tumor environment—dramatically improving the safety of radiopharmaceuticals.
- The lab offers an outstanding research environment with:

- Full facilities for organic synthesis, bioconjugation and radiochemistry
- HPLC-MS, preparative HPLCs, FPLC, NanoDrop UV
- BLI and NanoTemper systems for bioconjugate analysis
- NMR (400, 500, 600 MHz) spectrometers, MALDI-TOF, Orbitrap LC-MS mass spectrometers

**What We Offer**
- 18-month fully funded contract with potential for further collaboration
- Access to cutting-edge facilities and equipment
- Opportunities to publish, attend conferences, and grow your scientific network
- A welcoming team and vibrant scientific environment in Dijon, France

**Site web**:
**Poste et missions**:

- As a postdoctoral researcher, you will lead the design, synthesis and preclinical evaluation of functional probes and antibody-based bioconjugates. You will collaborate closely with chemists, radiochemists, biologists, radiopharmacists, and imaging specialists in a multidisciplinary and translational research setting.

**Your main responsibilities will include**:

- Designing and synthesizing bioconjugatable probes (incorporating various radiometal chelators and linkers)
- Developing and optimizing chemical and enzymatic bioconjugation protocols
- Purifying and characterizing organic molecules and bioconjugates (FPLC, HPLC, MS, UV, etc.)
- Designing preclinical studies and analyzing data
- Writing detailed experimental protocols, technical reports, and scientific publications

**Salary** : 32-35 k€ annually, depending on experience.

**Mobilité géographique**:

- Pas de déplacement

**Prise de fonction**:

- 01/10/2025

**Profil**:
**Minimum Qualifications**
- Ph.D. in organic chemistry (or closely related field)
- Strong experience in organic synthesis and chromatographic techniques (e.g., HPLC, HPLC-MS)
- Experience or solid understanding of bioconjugation and protein purification is a plus

**Preferred Skills**
- Experience in supramolecular chemistry, radiochemistry, nuclear imaging

**Personal Attributes**
- Independent, organized, and proactive
- Strong communication skills (written and oral)
- Collaborative mindset with the ability to work in a dynamic, interdisciplinary environment

**Objectifs**:
As a postdoctoral researcher, you will lead the design, synthesis and preclinical evaluation of functional probes and antibody-based bioconjugates.

You will collaborate closely with chemists, radiochemists, biologists, radiopharmacists, and imaging specialists in a multidisciplinary and translational research setting.

**Your main responsibilities will include**:

- Designing and synthesizing bioconjugatable probes (incorporating various radiometal chelators and linkers)
- Developing and optimizing chemical and enzymatic bioconjugation protocols
- Purifying and characterizing organic molecules and bioconjugates (FPLC, HPLC, MS, UV, etc.)
- Designing preclinical studies and analyzing data
- Writing detailed experimental protocols, technical reports, and scientific publications

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