Senior Computational Scientist

il y a 14 heures

Paris, Île-de-France BioTalent Temps plein

We are seeking a Senior Scientist to join our Protein & Vector Engineering team, contributing to cutting-edge research in structural bioinformatics, computational chemistry, and AI-driven drug design.

This role plays a key part in advancing computational drug design (CDD) across biologics, chemistry, and genomics programmes. You will work closely with senior scientists and cross-functional teams to develop and apply innovative computational approaches for 3D structure prediction, molecular modelling, and protein/antibody design.

What this role offers

  • Senior-level ownership of computational strategy and execution
  • Exposure to AI- and computation-driven drug discovery programmes
  • A collaborative, multidisciplinary environment across protein engineering, genomics, and data science
  • Opportunity to contribute to publications, patents, and platform development

Key responsibilities

  • Lead computational strategies for drug design, molecular modelling, and structural bioinformatics
  • Design and execute advanced workflows (MD, QM, protein & antibody design, AI/ML-driven CDD)
  • Mentor junior scientists and support technical development
  • Build and maintain robust, reproducible in-house computational pipelines
  • Collaborate with internal teams and external partners

What you'll bring

  • PhD in a relevant computational or life sciences discipline
  • 5+ years' experience in computational drug design or molecular modelling
  • Strong expertise in structural bioinformatics, computational chemistry, and AI/ML
  • Programming skills in Python, R, or Bash
  • Experience with tools such as Schrödinger, MOE, Rosetta, PyMOL, AlphaFold

Nice to have

  • HPC or cloud computing experience
  • Peptide modelling
  • End-to-end drug discovery exposure

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