Towards replacing animal models in biomedical research with 3D cellular models? An embedded ethical analysis
il y a 7 heures
Réf ABG-135232
Sujet de Thèse
22/01/2026
Financement de l'Union européenne
Université Angers
Lieu de travail
ANGERS - Pays de la Loire - France
Intitulé du sujet
Towards replacing animal models in biomedical research with 3D cellular models? An embedded ethical analysis
Champs scientifiques
- Santé, médecine humaine, vétérinaire
Mots clés
SSH, Health
Description du sujetOrganoids are advanced 3D models replicating organs or aspects of development, widely used in biomedical research. However, they raise ethical concerns, particularly with embryo and brain organoids. These models challenge traditional legal and ethical frameworks, especially as they are increasingly used as alternatives to animal models in research. Political pressure for reduced animal use is pushing regulatory changes, such as the FDA Modernization Act 2.0, to integrate in vitro models into clinical trials. Nantes University aims to lead in personalized and ...
More information :
Prise de fonction :01/10/2026
Nature du financementFinancement de l'Union européenne
Précisions sur le financementCofund MSCA Horizon Europe
Présentation établissement et labo d'accueilUniversité Angers
Today, there are urgent needs of profiles capable of understanding the medical challenges in their entirety rather than from a strictly health or social point of view. The Breath programme will fill that gap by training excellent researchers.
Breath is supported by the european programme Horizon Europe Marie Skłodowska-Curie and will recruit 20 talented fellows over two calls. The 20 applicants will have the opportunity to choose among 40 interdisciplinary projects at the intersection between health and Social Sciences and Humanities (SSH). Breath programme is carried by the University of Angers (UA) and the two others public universities in Pays de la Loire: University of Le Mans (LMU) and Nantes University (NU).
Doctoral Candidates (DC) will be systematically supervised by 3 co-supervisors: one expert from SSH, one from Health and one non-academic and/or international expert
The Breath programme is organised in two calls :
- One call to obtain high level research topics to offer to doctoral candidates
- One call to recruit doctoral candidates on the selected research topics
The Breath programme offers:
A unique experience fully funded during 36-month with attractive employment and salary conditions
Exceptional working and mentoring conditions
Excellent research training in English including a 3-month mandatory secondment
Elaborate training in transferable skills and personal career development support
Cofund Breath's key figures :
- Overall project duration: 5 years
- Duration of the PhD: 3 years
- Number of doctoral positions: 10 doctoral contracts fully funded from the 1st October 2026
- Overall cost: 6M euros, with co-financing by the European Commission of 2 million
Etablissement délivrant le doctorat
Nantes Université
Profil du candidatcan be of any nationality
should comply with the mobility rules: they must not have resided or carried out their main activity (work, studies, etc.) in France for more than 12 months in the 36 months immediately before the deadline of the call
can go on short term secondments (3 months)
must not have a doctoral degree
must settle in France
Date limite de candidature
12/03/2026
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