About Anthogyr
Since 80 years, Anthogyr designs and manufactures medical devices that are sold worldwide to assist healthcare professionals to treat their patients. Located in the Mont Blanc valley in the French Alps, Anthogyr does business on a human scale but addresses the global market as an implant manufacturer, with leading or challenging positions in France and rapid-growth markets such as China. Within the international group, we offer you the opportunity to grow in an innovative and professional environment in a dynamic team.

About The Role
Anthogyr is seeking for a qualified dentist with a strong commitment to science, research and innovation within the field. The position is part of the European Doctoral Network "SHIELD" (Strategies for Healing Implant-associated infections and Enhancing Longevity in Devices). SHIELD offers an exciting opportunity for early-career researchers to contribute to transforming the management of infections associated to medical implants. Focused on addressing the challenges posed by implant-associated infections (IAIs), SHIELD aims to deepen our understanding of IAI mechanisms and develop innovative antibacterial biomaterials to improve patient outcomes.

The start date will be in early March at the latest.

Objectives

The PhD student will work on a PhD project aiming to prepare and characterize innovative surfaces treatments on dental implants and evaluate the clinical performance of biomimetic and personalized macroscopic designs for soft-tissue healing. The project will be conducted using in vitro models in collaboration with leading universities (University of Gothenburg and University of Oslo). These approaches will be ultimately evaluated through clinical trial in a very close collaboration with Hospices Civils de Lyon, France, where the PhD candidate will be registered and co-supervised by senior researchers from University of Lyon.

Research activities include

• Characterization of innovative, nanostructured surfaces
• Simulating biofilm model/host interactions via a flow cell co-culture system
• Assessing the effectiveness of customised, anatomically shaped devices using in vitro and/or in vivo models
• Develop and conduct an interventional study protocol on patients to compare the most effective nanostructured surface with a polished reference surface at individual implant sites

Training and mobility

• The PhD student will be required to work on different sites:
• Anthogyr, Sallanches, France
• Hospices Civils de Lyon, Lyon, France

• He/she will participate to research secondments at SHIELD partner institutions:

• University of Gothenburg, Sweden

• University of Oslo, Norway
• He/she will take part in specialized training workshops and international congress

Required Education Level

• Research field: Medical Sciences and Dentistry
• Education Level: Dentistry Degree or Master's Degree or equivalent

Skills/Qualifications/Specific Requirements

• Applicants have gone through a dentistry career path with a first experience in research
• They should hold a Master's degree or equivalent in microbiology, biotechnology or medical sciences or similar providing access to PhD programs and should have experience with experimental research and dentistry/implantology
• Applicants must have excellent proficiency in written and spoken English
• They also should have a good French speaking
• Strong motivation and ability to collaborate in an interdisciplinary and international teams

Appointment & Benefits

The appointment will be on a temporary basis for a maximum period of 36 months (PhD student, regular full-time employment contract), with an attractive salary plus allowances package.

Eligibility criteria

• PhD researchers who have successfully defended their doctoral thesis but who have not yet formally been awarded the doctoral degree are not eligible.
• Career stage: applicants must be within the first 4 years (full-time equivalent) of their research careers at the date of recruitment (measured from the degree obtention date) to be eligible
• International mobility: candidates must not have resided or conducted their main activity (work, studies…) in France for more than 12 months within the 3 years immediately preceding their recruitment.

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