INTERNSHIP - R&D project manager assistant

il y a 6 jours

Montreuil, Île-de-France 4Dcell Temps plein

R&D project manager assistant - Internship

Unlock the Future of Drug Discovery.

Join 4Dcell and become part of a pioneering French biotech on a mission to transform drug discovery and toxicology. We're engineers and biologists united by a single goal: to replace animal testing with intelligent, in vitro "organ-in-a-well" models that deliver unprecedented predictive power to drive tomorrow's therapies.

4Dcell has developed two flagship solutions: the SmartHeart Platform, which recreates human ventricular tissue in a standard 96-well plate, and the first-in-class SmartSphero Technology, enabling the generation of a wide range of organoids.

You'll collaborate with leading biophysicists, engineers, and biologists to tackle the toughest health challenges, from heart failure and immuno-oncology to pancreas and renal diseases. We combine ambition with a supportive, curiosity-driven culture.

Why intern with us?


• Freedom and responsibility to structure and lead your own projects


• Hands-on exposure to game-changing technologies


• Apply marketing skills on a new, growing, exciting and revolutionary market


• A team that values collaboration, growth, and fun


• Membership in a high-energy, fast-growing team developing truly game-changing, high-tech products


• The opportunity to navigate both a commercial start-up environment and an R&D scientific setting


• Close collaboration with experts in technology, marketing, sales, application science and operations


• Step into a role where your work accelerates drug discovery, improves patient outcomes, and builds amore ethical pharmaceutical future.

Context

Within our R&D team, you will work hands-on with experimental protocols to characterize cardiac pathologies and cardiac cell line maturation.

Main Responsibilities

Executing Design of Experiments (DoE)


• Prepare culture media and reagent dilutions


• Seed cells at defined densities according to the DoE matrix


• Record all steps and observations in the lab notebook (LIMS/Excel)Data

Processing & Analysis


• Import raw metrics (viability, marker expression, contractility)


• Create summary tables and plots to compare conditions


• Draft concise experimental summaries with actionable conclusions

3D Cell Culture


• Set up cardiac organoid (SmartHeart)


• Conduct immunofluorescent staining and confocal imaging


• qPCR analysis

Deliverables


• Complete experimental records (DoE details, raw results, observations)


• Analyzed datasets with clear graphical outputs


• Updated operational protocols


• Brief reports for each experimental campaign

Environment & Tools


• Equipment: CO₂ incubators, laminar-flow hoods, confocal microscope


• Software: LIMS/Excel, GraphPad Prism, R or basic Python notebooks


• Techniques: DoE, 2D & 3D cell culture, immunofluorescence

Candidate Profile


• Master's student in Biology, Biotechnology or Biomedical Engineering


• Hands-on experience with cell culture (2D and/or 3D)


• Comfortable with data entry and analysis


• Experienced in Molecular Biology


• Organized, experimentally rigorous and proactive


• Good technical English

Duration & Terms


• 6-month internship, starting January or February 2026


• Based in Montreuil (Paris), France

Legal internship stipend 650€ + partial transport reimbursement

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