Researcher (M/W) multi-step organic synthesis
il y a 1 semaine
10 Dec 2023
Job Information
Organisation/Company
CNRS
Department
Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé
Research Field
Chemistry
Physics
Technology
Researcher Profile
First Stage Researcher (R1)
Country
France
Application Deadline
30 Dec 2023 – 23:59 (UTC)
Type of Contract
Temporary
Job Status
Full-time
Hours Per Week
35
Offer Starting Date
1 Feb 2024
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The researcher (M/W) will be responsible for carrying out the design, retrosynthesis, and multi-step organic syntheses of multifunctional organic molecules. He will be responsible for the purification and characterization of the compounds prepared by the usual techniques such as 1D NMR, 2D NMR, MS, IRFT, HPLC/MS, GC/MS. His mission will be to participate in the in vitro biological evaluation of the synthesized compounds. The mission will also include the optimization of protocols for the synthesis of the most biologically promising compounds on a scale of several grams, for in vivo evaluation.
– Bibliographic search
– organic chemical synthesis of molecules of interest
– characterization of organic molecules by 1D NMR spectroscopy 1H, 13C, 19F, 31P; 2D NMR; MS; IR, UV/Vis.
– kinetic monitoring and quantitative dosage of metabolites and transformation/reaction products of compounds of interest by HPLC-MS, GC-MS, etc.
– additional bibliographic work
– Writing summary report
– Presentation of the results
– Writing publications
The Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé (ICPEES), a joint research unit under the joint supervision of the CNRS and the University of Strasbourg (UMR7515). Its staff is made up of around fifty permanent employees and some 80 PhD students, post-docs and other fixed-term contracts. The institute boasts world-renowned expertise in chemistry, materials development and characterization by various processes, as well as strong industrial collaborations.
The researcher (M/F) will join the Nanomaterials, Catalysis and Interfaces team at ICPEES, reporting to Dr. Rachid BAATI.
The project is part of a high-potential valorization project (Projet de Prématuration CNRS). The work carried out will enable us to advance the technological maturity of the best active molecules in a significant way.
Requirements
Research Field
Chemistry
Education Level
PhD or equivalent
Research Field
Physics
Education Level
PhD or equivalent
Research Field
Technology
Education Level
PhD or equivalent
Languages
FRENCH
Level
Basic
Research Field
Chemistry
Years of Research Experience
None
Research Field
Physics
Years of Research Experience
None
Research Field
Technology
Years of Research Experience
None
Additional Information
Eligibility criteria
– Organic chemistry, analytical chemistry, parallel microwave synthesis
– Organic synthesis, multistep synthesis and physicochemical characterization of compounds by NMR, IR, MS.
– Analytical chemistry: LC/MS, GC/MS
– General notion of UV/Vis spectroscopy (detection and quantitative dosage)
– Have already handled/used HPLC or GC devices during the thesis project and work experience
– Concept of enzymology
– Knowledge and mastery of chemical research databases
– Have worked in a multidisciplinary environment at the interface of chemistry and biology
– Having supervised students (masters, undergraduate)
– Writing and oral skills for presenting/commenting/analyzing results in French and English
– Ease of integration into a research team
– Know how to work in a multidisciplinary environment
– Know how to work and collaborate in a team
– English level C1 or C2 according to the Common European Framework of Reference for Languages (indicate TOEIC level or equivalent).
.
Website for additional job details
Work Location(s)
Number of offers available
1
Company/Institute
Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé
Country
France
City
STRASBOURG
Geofield
Where to apply
Website
Contact
City
STRASBOURG
Website
STATUS: EXPIRED
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