Postdoctoral Research Assistant Position in
Il y a 2 mois
Created in 1964, Inserm is a public scientific and technological institution, placed under the dual supervision of the Ministry of Health and the Ministry of Research. Dedicated to biological, medical and human health research, it is positioned along the entire route from the research laboratory to the patient's bedside. On the international scene, it is the partner of the largest institutions involved in the challenges and scientific progress of these fields.
**Poste et missions**:
**General background**:
**The activities include**:
- Developmental (DNT) and acute (ANT) neurotoxicity are currently assessed via different OECD guideline studies. DNT/ANT guideline studies are extraordinarily resource-intensive and therefore not suited for studying adverse effects of large numbers of chemicals. DNT guideline studies are not mandatory and ANT testing is not performed for low tonnage compounds. There is international consensus, strongly supported by EFSA and the OECD, that DNT testing has to be made faster and more human-relevant by implementing an alternative DNT testing battery for regulatory purposes. The key strategy is to provide a comprehensive battery of NAMs that for DNT fills the gaps in the current DNT in vitro battery and, for ANT, sets up such a battery, both according to DNT/ANT modes-of-action. The recruited researcher will contribute to PARC work package 5.2**Mobilité géographique**:
- Européenne**Télétravail**:
- Occasionnel**Prise de fonction**:
- 24/04/2023**Profil**:
**Requirements**:
- **University degree **(PhD in biology/biochemistry, that may not have been completed since more than five years.
- **Expertise **in toxicology, neuroscience, and in the use of the zebrafish model would be an advantage.
- Excellent communication and organization skills.
- Good knowledge of written and spoken English skills (French is not mandatory but would be an advantage).
- A conscientious work ethic, flexibility and the ability to work in a team.
**Objectifs**:
The post-doc will contribute to the development and use of innovative methodologies that will directly aid chemical hazard identification and regulation using early developmental stages of zebrafish. This animal is an alternative whole-organism, low-cost screening tool with integrated nervous system functions.
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