Cdd (M/F) Researcher in Organic Synthesis - 18

Il y a 2 mois


Nice, France CNRS Temps plein

Cette offre est disponible dans les langues suivantes:

- Français
- Anglais

Date Limite Candidature : mercredi 2 octobre 2024 23:59:00 heure de Paris

**Informations générales**:
**Intitulé de l'offre **:CDD (H/F) Chercheur en synthèse organique - 18 mois - Chimie Médicinale - développement d'antibiotiques**
Référence : UMR7272-CYRRON-001
Nombre de Postes : 1
Lieu de travail : NICE
Date de publication : mercredi 11 septembre 2024
Type de contrat : CDD Scientifique
Durée du contrat : 18 mois
Date d'embauche prévue : 1 novembre 2024
Quotité de travail : Temps complet
Rémunération : entre 3021.50 et 4208.37 € bruts mensuels selon expérience
Niveau d'études souhaité : Niveau 8 - (Doctorat)
Expérience souhaitée : Indifférent
Section(s) CN : Chimie du vivant et pour le vivant : conception et propriétés de molécules d'intérêt biologique

**Missions**:
Les missions sont l'identification et la validation du mécanisme d'action d'une classe d'agents antibactériens, l'établissement du profil pharmacologique de composés tête de série et le suivi, l'analyse des données chimiques, biologiques et pharmacologiques en rapport avec le projet, le support à la gestion du projet.

**Activités**:

- conception, synthèse et caractérisation de molécules bioactives et d'outils moléculaires (tâche principale, responsabilité)
- réalisation d'analyses biochimiques pour la compréhension du mécanisme d'action (tâche principale, responsabilité)
- Initiation des études pharmacologiques de composés tête de série (tâche principale, en co-responsabilité)
- gestion de projet (tâche principale, responsabilité)
- analyse et interprétation des données pharmacologiques (tâche secondaire, en coresponsabilité)

**Compétences**:

- très bonnes compétences en synthèse organique, notamment de composés hétérocycliques et d'outils moléculaires dérivés (sondes), incluant réactivité, purification et caractérisation des produits synthétisés
- connaissances spécifiques des mécanismes d'action des antibiotiques et de leur détermination par des méthodes biochimiques ou bioanalytiques
- compétences de base en gestion de projet
- compétences de base en pharmacologie (formation interne au cours du contrat possible)

**Contexte de travail**:
**Contraintes et risques**:
Il n'y a pas de contraintes et risques particuliers en dehors de ceux inhérents à la pratique de la synthèse organique.



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