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Research Technician, High Throughput

Il y a 4 mois


Grenoble, France European Molecular Biology Laboratory Temps plein

Research
- Grenoble, France

We are looking for a Research Technician to join Marquez Team in the EMBL Grenoble Unit.

EMBL Grenoble specializes in fundamental research in structural biology, and in developing state-of-the art instrumentation, methods and services. The site is located on the dynamic European Photon and Neutron science campus (EPN campus), together with other international and French research institutions.

The Marquez team has a strong focus on technology and methods development in macromolecular crystallography and operates the High Throughput Crystallization Laboratory (HTX Lab) at EMBL Grenoble. The HTX lab is one of the largest platforms for automated macromolecular crystallization screening in Europe and is offering advanced crystallography services to users in academia and industry worldwide.

Your role

You will cooperate with other team members towards the operation of the HTX facility, further development of our automated crystallography and fragment screening pipelines and will contribute to research projects. Your responsibilities will include:

- Operation of the automated crystallography platform comprising automated liquid handling, imaging and crystal harvesting robotic systems. Liaising with HTX lab users.
- Contributing to further development of automated crystallography pipelines for fragment screening based on the CrystalDirect technology and the CRIMS software within the framework of the EC funded projects, including the Fragment Screen project.
- DNA cloning, protein expression and purification and protein crystallography will be performed as part of the internal research projects.
- Management of orders and consumables for the HTX laboratory and general management and maintenance of robotic equipment (arranging with external companies for repairs when necessary).
- Participation in research projects in cooperation with other members of the team, including fragment screening on targets of biomedical or biotechnological relevance.

**Closing date**: 2 January 2024

Contract duration: 3 years

Grading: 4, 5 or 6 depending on experience and qualifications

Reference number: GR00220

You have
- A degree in biochemistry (Masters, Bachelor degree or equivalent) or a related field from a technical school or university.
- Skills in protein production for structural studies and in protein crystallization as well as the use of robotic laboratory equipment.
- Experience in diffraction data collection or fragment screening.
- The ability to work within a team and communicate with users of the crystallization facility is essential.
- Motivation to acquire further skills and contribute to the development of new methods.
- Desire to work in an international environment and to contribute to high quality research and services.
- Fluency in English and good computer skills.

You might also have
- Experience in structural analysis through macromolecular crystallography, ligand screening or the analysis of small molecule-protein interactions.

Why join us

EMBL is curiosity-driven, community-oriented and international. As an inclusive, equal opportunity employer, we believe that diversity enables us to collaborate more effectively and be innovative in our approaches. We are, therefore, committed to creating an inclusive and flexible culture - one where everyone can realise their full potential and make a positive contribution to our organisation.

EMBL offers attractive conditions and benefits appropriate to an international research organisation with a very collegial and family-friendly working environment. Competitive salary and social security benefits, financial support for relocation, a relaxed culture, professional development, canteen and other staff facilities make EMBL a great place to work.

What else you need to know

We are Europe’s research laboratory for the life sciences - an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international, innovative and interdisciplinary laboratory with more than 1900 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome.

Our mission is to offer vital services in training scientists, students and visitors at all levels; to develop new instruments and methods in the life sciences and actively engage in technology transfer activities, and to integrate European life science research. The working language of the institute is English.

Please note that appointments on fixed term contracts can be renewed up to 9 years in total, depending on circumstances at the time of the review.

EMBL is a signatory of DORA. Find out how we implement best practices in research assessment in our recruitment processes here.