Development of An Organic Optical Sensor Platform
Il y a 2 mois
**Development of an organic optical sensor platform for detection of in vitro bioluminescence activities**:
- Réf
- **ABG-111547**
- Sujet de Thèse- 28/02/2023- Contrat doctoral- Ecole de Mines de Saint-Étienne- Lieu de travail- Gardanne - Provence-Alpes-Côte d'Azur - France- Intitulé du sujet- Development of an organic optical sensor platform for detection of in vitro bioluminescence activities- Champs scientifiques- Matériaux
- Chimie
- Electronique
- Mots clés-
**Description du sujet**:
- The aim of this project is the development of novel organic optical sensors for the detection of bio
- and chemi-luminescence of cell activities
- _in vitro_. This project consists of two objectives. The first one is the development of a multi-pixel organic photodetector array for cell activity detection and proper electronics for connecting to recording equipment. The second objective is to demonstrate the proof of concept of detecting bio
- and chemi-luminescence using these devices.- In the first phase, the student will develop the device in a fully equipped cleanroom, containing all the necessary microfabrication technologies. This will be in parallel to the device characterization for understanding its performance.- In the second phase, the student will work on an optimal electronic packaging to connect the device to recording equipment. Then, he will carry on cell culture and will study the device performance
- _in vitro_ for recording bio
- and chemi-luminescence cell activities.- Publications from the group relevant to the project: Rezaei-Mazinani S. et al. Monitoring intrinsic optical signals I brain tissue with organic photodetectors, Adv. Mater. Technol., 2018. Rezaei-Mazinani S. et al. Monitoring fluorescent calcium signals in neural cells with organic photodetectors, J. Mater. Chem. C, 2019.- The student will be fully supported on data analysis aspects of the project. Basic trainings for cell culture,
- _in vitro_ experiments and imaging will be provided in Bioelectronics department.**Prise de fonction**:
- 01/09/2023**Nature du financement**:
- Contrat doctoral**Précisions sur le financement**:
**Présentation établissement et labo d'accueil**:
- Ecole de Mines de Saint-ÉtienneThe department of bioelectronics at the Centre Microélectronique de Provence is a pioneering lab in in the interdisciplnary field of organic bioelectronics. We have access to a 700 m2 cleanroom facilities and have highly equopped labs for development of neural interfacing devides.
**Site web**:
**Intitulé du doctorat**:
- Doctorat en Microélectronique - option Bioélectronique**Pays d'obtention du doctorat**:
- FranceA good understanding of electronic circuits, electrical characterization and signal processing using Matlab is mandatory.
The knowledge of English language is essential.- 05/05/2023
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