Postdoctoral Scientist

**Site web**:
**Poste et missions**:

- Cardiac myocytes have a surface membrane and a dense network of transverse tubules (TT), which are invaginations of the surface membrane that penetrate deep into the cell interior. Many membrane proteins are localized in both the surface and TT membranes: this is the case for ß-adrenergic receptors. Our goal is to explore the function of ß-adrenergic receptors in these two membrane compartments. The experiments will be performed in isolated ventricular myocytes from both male and female animals. The 4-year project funded by ANR (Agence Nationale de la Recherche) involves three other laboratories involved in physical chemistry, biochemistry and molecular modelling, all located close to our lab. The budget finances a full-time scientist position at UMR-S 1180, starting as soon as 1st February 2024 and lasting for 30 months.**Mobilité géographique**:

- Pas de déplacement**Prise de fonction**:

- 03/02/2025**Profil**:

- Applicants should have a PhD and (ideally) a few years of postdoctoral experience. A background in cardiac electrophysiology and/or fluorescent microscopy is desirable. Independence and strong motivation are required. The job will require skills in cell physiology, microscopy, patch-clamp, single cell contractility, protein expression/purification, biochemical assays, cell culture, etc., as well as data analysis and science communication. Fluency in English is required.**Objectifs**:

- We offer the special opportunity to contribute to an exciting new interdisciplinary scientific project. The postdoc will benefit from all laboratory expertise as well as from a large number of core facilities._ _Our worldwide collaborative network is substantial and offers many opportunities for professional development. The salary will depend on qualifications and professional experience and is calculated in accordance with INSERM salary scales.