Postdoctoral Researcher in Mass Spectrometry
Il y a 2 mois
**Date de parution**:17 sept. 2024**Ville**:GIF SUR YVETTE**Pays/Région**:FR**Type de contrat**:Post-doc**N° offre**:6860Postdoctoral Researcher in Mass Spectrometry Imaging F/M
- Nous sommes un groupe pharmaceutique à dimension humaine, international et indépendant, gouverné par une Fondation. Notre modèle, singulier, fait notre fierté mais, surtout, nous permet de servir pleinement notre vocation : « engagés pour le progrès thérapeutique au bénéfice des patients ». Aujourd’hui leader mondial en cardiologie, nous avons choisi de devenir un acteur focalisé et innovant en oncologie d’ici 2030, en ciblant des cancers difficiles à traiter et en y consacrant plus de 70 % de notre budget R&D. Un défi que nous poursuivons en parallèle du développement de notre activité générique pour un accès à des soins de qualité pour tous, et à moindre coût.
Venez vivre et contribuez à faire vivre notre engagement #MovedByYou- 18-month post-doc position with an expected starting on October 1st,2024.-
- This project will be divided in 3 main work packages:
- WP1: Atlas of detectable endogenous metabolites.- The aim of the WP is to build an atlas of detectable endogenous metabolites in various tissues using the different instruments and methods available at Servier.-
- WP2: Implementation of new tools for biodistribution studies by MSI-
- WP3: Imaging of brain/tumor organoids coculture in collaboration with Institut Goustave Roussy.- To image the metabolic and lipidic change occurring during neural cell differentiation and tumor invasion, a collaboration with IGR is currently being set up to perform some MALDI experiment (method development and image acquisition) on brain organoids.-
- Responsabilities:
- Build an atlas of endogenous metabolites to elaborate a decision tree for the selection of the right MSI technology in upcoming projects
- Implement new technology in our internal platform such as Myralys® technology
- Technical responsibilities of lab instrument in interaction with team’s scientists and instrument manufacturer engineer
- Ensure good communication with other partners to support projects involving MSI
- Participate to the BioTransformation and BioDistribution team activities
- Qualification:
- PhD in analytical chemistry or related discipline- Hard skills:
- Mass Spectrometry Imaging (mandatory)
- High Resolution Mass Spectrometry of small molecules (Spatial) Metabolomics
- Data processing (SCiLS)
- Skills in programing and large molecule analysis (e.g.: Antibody Drug Conjugates, Oligonucleotides...) would be a plus
- Soft skills:
- Autonomy, scientific rigor, critical mind
- Ability to innovate, bring forward new proposals.
- Excellent communication, interpersonal skills
- Good listening and writing skills in English (presentations, scientific papers)
- Ability to work and collaborate with internal and external partners
- Leadership skills:
- Ability to share his knowledge with technician and scientists
-
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