Trainee in Rna Structural Dynamics

Il y a 2 mois


Paris, France Qubit Pharmaceuticals Temps plein

Drug discovery through simulation and modeling requires unprecedented computational capabilities beyond the petaflop, or more than one million billion operations per second. Qubit Pharmaceuticals, a deeptech company, has worldwide access to existing and emerging supercomputers with one of the largest private GPU supercomputers for life sciences in France. Our in-house platform Atlas integrates advanced simulation technologies that run on these supercomputers to accelerate calculations by a factor of 100 000, thus performing calculations in a few hours versus over a year's time. These simulations, along with optimized small molecule identification strategies and in-house experts in computational and medicinal chemistry, will allow several chemical series to be explored in parallel.

Qubit Pharmaceuticals is looking for a **trainee in RNA Structural Dynamics (M/F)** for the RNA platform for Drug Discovery.

RNA is a key regulator of almost every cellular process, and the structures adopted by RNA molecules are central to their functions. It is important to describe the dynamic ensemble of RNA because it reflects the true structural nature of the molecule, and enables describing and predicting key steps in RNA-mediated processes that involve conformational change that cannot be accurately modelled based on static RNA structures. Computer simulations, and in particular atomistic molecular dynamics (MD), allow structural dynamics of biomolecular systems to be investigated with unprecedented temporal and spatial resolution, and are essential to understand and complement experimental investigations of RNA structural dynamics

**The perfect fit for this job**

**Your role**
- Molecular dynamics simulations
- Structural dynamics analysis
- Conformational space exploration
- Free energy simulations

**Your Qualifications**
- Hold a 4-year university degree (either a "Maîtrise", 1st-year Master's (M1), Engineering School diploma, ENS Academic Institution, etc. or equivalent) M2 with a major related to the requested specialization.
- Skills in Chemistry, biochemistry and life sciences - molecular modelling
- Unix usage
- Very good knowledge of written and spoken English
- Good communication skills

**The proposal benefits & perks**
- Duration: 6 months internship
- Starting date: From february 2025
- Lunch vouchers worth €9 covered at 50%
- Location: Paris 14th arrondissement

**Join our journey to push the frontiers of science, technology and your career**
- “At Qubit Pharma, we don't just dream big—we turn those dreams into real-life innovations in the Drug Discovery world. That's what makes this more than a job - it's a journey where your best ideas can turn into disruptive and game-changing realities."_
- Yassine, Atlas Team
- “Join Qubit Pharma for a multicultural, multidisciplinary environment that fuels growth. We're a team where diverse perspectives converge, offering scientists and experts like you the opportunity to cultivate expertise and contribute to groundbreaking discoveries."_
- Daniele, Research Team

**Qubit mission vision and values**

**A unique career**

Qubit Pharmaceuticals is looking for talented professionals to join our team - individuals who have a passion for science, drug discovery and molecular modeling.

**Our Vision**

Unlock the power of quantum at scale to design better treatments for any target and every patient.

**Our Mission**

We pioneer quantum-aided drug design and leverage cutting-edge science to design novel molecules for complex targets.

**Workplace and culture**

We're a diverse mix of expertise, experience and perspectives, united around the passion to make a positive impact in drug design and discovery using the best computational technology.

We’re proud of our inclusive culture where individuals are encouraged to collaborate, lead and grow.

**Our Values**

We live and work by our values:

- We care genuinely
- We encourage diversity
- We value scientific excellence
- We foster resilience
- We succeed together



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