Postdoctoral Position in Asymmetric Heart
Il y a 3 mois
**About us**:
The _Imagine_ Institute (IHU, ‘Institut Hospitalo-Universitaire’, INSERM U1163) is a recent research structure located within Necker Children’s Hospital (Paris).
Its research labs are focused on understanding the molecular mechanisms of genetic diseases that affect the adaptive and innate immune systems, the skeletal dysplasia, the nervous system, stem cell differentiation, kidney physiology, metabolism, etc.
**Mission**:
A Postdoctoral position in asymmetric heart morphogenesis is open in the Imagine-Institut Pasteur Unit of Heart Morphogenesis, Paris, France
**Keywords**: left-right asymmetry, heart development, 3D morphogenetic mechanisms, quantitative image analysis, transcriptomics, mouse genetics, interdisciplinary collaborations
The heart functions in two parallel but asymmetric circuits, in which the right and left ventricles drive the pulmonary and systemic circulations, respectively. In the heterotaxy syndrome, abnormal left-right patterning of the embryo leads to a spectrum of severe structural heart defects, the heterogeneity of which remains puzzling. Whereas the molecular cascade breaking the bilateral symmetry of the early embryo has been well characterised, how asymmetry is sensed by organ-specific precursor cells to control organogenesis remains poorly understood. The Meilhac lab uses mouse as a model to elucidate basic mechanisms of asymmetric heart morphogenesis, uncover novel genetic players and explore how this relates to congenital heart defects in patients.
Previous work in the lab has characterized mouse models of heterotaxy and generated a large transcriptomic dataset to screen for novel asymmetric factors. A challenge is to understand their function at specific asymmetric steps of heart morphogenesis. The project will exploit interdisciplinary expertise at the forefront of developmental biology, computational science and pediatric cardiology. Using cutting-edge technologies in omics, mouse genetics and quantitative 3D imaging, the project will provide novel insights into basic morphogenesis mechanisms, while deciphering pathological processes in the heart, potentially relevant to other asymmetric visceral organs.
**Location**: our lab is located at the Institut _Imagine_, within the hospital Necker-Enfant Malades, and is part of the Dept of Developmental and Stem Cell Biology of the Institut Pasteur, which together offers a vibrant multidisciplinary and international research environment with state-of-the art technological platforms, downtown Paris.
**The postdoctoral position is funded for 3 years by the FRM and is open ASAP.**
**Profile**:
**Expected profile**:
- After a PhD in Life Sciences, you have a strong interest in developmental biology ;
- Your previous research experience is solid in molecular biology or genetics ;
- You value animal models ;
- You work with rigour and creativity and enjoy team work.
To apply, please send a cover letter, CV and contact details of 3 references
-
Paris, France France - BioImaging Temps pleinPostdoctoral position on cellular morphogenesis using high-resolution fluorescence microscopy (Paris, France) We are looking for a highly motivated postdoctoral candidate with a background in biophysics, physics, engineering, or chemistry to measure the dynamics of cell-envelope biogenesis in live bacteria at the single-protein level using high-resolution...
-
Paris, France France - BioImaging Temps pleinPostdoctoral position on cellular morphogenesis using high-resolution fluorescence microscopy (Paris, France)We are looking for a highly motivated postdoctoral candidate with a background in biophysics, physics, engineering, or chemistry to measure the dynamics of cell-envelope biogenesis in live bacteria at the single-protein level using high-resolution...
-
Postdoctoral Researcher in Cognitive Neurosciences
Il y a 7 mois
Paris 13e, France ICM Institut du Cerveau Temps plein**Project summary**. Our aim is to investigate the spatiotemporal dynamics of word and number perception in both visual and auditory modalities. We will focus on brain specialization and the interplay between "bottom up" visual input and "top-down" influences from distant brain areas. This project utilizes a combination of magnetoencephalography (MEG) and...
-
Postdoctoral Position
Il y a 3 mois
Paris 5e, France CNRS Temps pleinCette offre est disponible dans les langues suivantes: - Français - Anglais Date Limite Candidature : vendredi 8 novembre 2024 23:59:00 heure de Paris **Informations générales**: **Intitulé de l'offre **:Postdoctoral Position (H/F) in Mechanics of mammalian development** Référence : UMR3215-JEAMAI-006 Nombre de Postes : 1 Lieu de travail : PARIS...
-
Postdoctoral Position
Il y a 3 mois
Paris, France CGenetix Temps plein**Regular travel required** Regular travels are mandatory for this job position between Paris (France) and Leiden (Netherland) during the first 12 months of the mission. **Full job description** **HOW MIGHT YOU DEFY IMAGINATION?** You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How...
-
Postdoctoral Position On Fgfr3-related Disorders
Il y a 3 mois
Paris, France Institut Imagine Temps plein**About us**: The _Imagine_ Institute (IHU, ‘Institut Hospitalo-Universitaire’, INSERM U1163) is a recent research structure located within Necker Children’s Hospital (Paris). Its research labs are focused on understanding the molecular mechanisms of genetic diseases that affect the adaptive and innate immune systems, the skeletal dysplasia, the...
-
Postdoctoral Research Scientist
il y a 1 jour
Paris, Île-de-France Hôpital Fondation Adolphe de Rothschild Temps pleinGenetic Epidemiology Postdoctoral PositionWe are seeking a highly motivated postdoctoral researcher to join our team at Hôpital Fondation Adolphe de Rothschild, a leading research hospital in ophthalmology and neurology. The successful candidate will be part of the BRAIN team, which focuses on advancing knowledge of ocular and cerebral disease.The primary...
-
Postdoctoral Position in Immunology
Il y a 3 mois
Paris, France Institut Imagine Temps plein**About us**: The _Imagine_ Institute (IHU, ‘Institut Hospitalo-Universitaire’, INSERM U1163) is a recent research structure located within Necker Children’s Hospital (Paris). Its research labs are focused on understanding the molecular mechanisms of genetic diseases that affect the adaptive and innate immune systems, the skeletal dysplasia, the...
-
Sales Manager Rebel at Heart
Il y a 6 mois
Paris, France Thomas Sabo Temps pleinTHOMAS SABO est une marque lifestyle internationale de bijoux, montres et accessoires. Créé en 1984, le groupe dispose de plus de 30 points de vente en France. C’est en phase avec une vision de la mode vivante et plurielle que nous vivons, que nous travaillons et cela se retrouve aussi dans nos collections. Le style de nos collections de bijoux et de...
-
Postdoctoral Researcher
Il y a 9 mois
Paris, France Meta Temps plein**Postdoctoral Researcher (PhD) Responsibilities**: - Perform research to advance the science and technology of intelligent machines - Perform research that enables learning the semantics of data (images, video, text, audio, and other modalities) - Devise better data-driven models of human behavior - Contribute research that can be applied to Facebook...
-
Postdoctoral Position in Immunology
Il y a 7 mois
Paris, France Institut Imagine Temps plein**About us**: The _Imagine_ Institute (IHU, ‘Institut Hospitalo-Universitaire’, INSERM U1163) is a recent research structure located within Necker Children’s Hospital (Paris). Its research labs are focused on understanding the molecular mechanisms of genetic diseases that affect the adaptive and innate immune systems, the skeletal dysplasia, the...
-
Multilingual Marketing And Sales Positions In Barcelona
il y a 3 semaines
Paris, France Cross Border Talents Temps pleinMultilingual Marketing and Sales Positions in Barcelona Location: Barcelona Spain Positions Available: Entry and MidSenior Level Languages Required: German Dutch Danish Swedish Norwegian French Are you a dynamic professional with a passion for marketing and sales We are looking for talented individuals who speak German Dutch Danish Swedish Norwegian or...
-
Postdoctoral Position
Il y a 3 mois
Paris, France Institut Imagine Temps plein**About us**: The _Imagine_ Institute (IHU, ‘Institut Hospitalo-Universitaire’, INSERM U1163) is a recent research structure located within Necker Children’s Hospital (Paris). Its research labs are focused on understanding the molecular mechanisms of genetic diseases that affect the adaptive and innate immune systems, the skeletal dysplasia, the...
-
Postdoctoral Researcher, Code Generation
Il y a 6 mois
Paris, France Meta Temps pleinMeta is seeking a Postdoctoral Researcher to work on innovative approaches to code generation with LLMs at FAIR (Fundamental AI Research). We publish groundbreaking papers and release frameworks/libraries that are widely used in the open-source community. We closely collaborate with other organizations at Meta to bring the latest research findings to...
-
Postdoctoral Researcher
il y a 6 jours
Paris, France Meta Temps plein**Postdoctoral Researcher - Reinforcement Learning Responsibilities**: - Collaborate on research to advance reinforcement learning agents to learn general models that can be used to solve a wide range of problems with little to no retraining - Devise, implement, and test new algorithms for unsupervised RL. - Influence progress of relevant research...
-
Postdoctoral Researcher
il y a 6 jours
Paris, France Meta Temps plein**Postdoctoral Researcher - Reinforcement Learning Responsibilities**: - Collaborate on research to advance reinforcement learning agents to learn general models that can be used to solve a wide range of problems with little to no retraining - Devise, implement, and test new algorithms for unsupervised RL. - Influence progress of relevant research...
-
Post-doctoral Position in Immunologie
Il y a 6 mois
Paris 5e, France INSTITUT CURIE Temps pleinThe department of Immunology headed by Ana-Maria Lennon-Duménil is actively looking for a Post-doc motivated to work on an ambitious project in translational Immunology. **Job description**: **Profile**: **Mission**: **Knowledge** - Experience in management and manipulation of human samples - Experience in cell culture and _in vitro_ experiments -...
-
Software Engineer Position in Paris
il y a 4 semaines
Paris, Île-de-France Wiremind, SAS. Temps pleinWiremind, SAS is a self-financed startup that has been transforming transport and events with a 360° approach combining UX, software, and AI since 2014. We optimize and market our clients' capacity on projects like ticket forecasting, 3D air freight optimization, and competitor price scraping. Our applications are used by companies like SNCF, United...
-
Postdoctoral Researcher in Neuronal Evolution and
Il y a 2 mois
Paris 13e, France CNRS Temps pleinCette offre est disponible dans les langues suivantes: - Français - Anglais Date Limite Candidature : mardi 19 novembre 2024 23:59:00 heure de Paris **Informations générales**: **Intitulé de l'offre **:CDD postdoc en évolution et développement des systèmes nerveux (H/F)** Référence : UMR7592-NIKKON-011 Nombre de Postes : 1 Lieu de travail : PARIS...
-
Senior Developer Position in Paris
il y a 1 jour
Paris, Île-de-France RED Global Temps pleinCompany OverviewRED Global is a dynamic and innovative company seeking an experienced developer to join our team. Our organization values creativity, collaboration, and excellence.SalaryThe estimated annual salary for this position is approximately €55,000 - €65,000, depending on experience and qualifications. This compensation package reflects the...
