Engineer in biology

il y a 1 semaine


Paris, France Institut Curie Temps plein

Join to apply for the Engineer in biology (F/M) role at Institut Curie. Institut Curie is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness. Missions Our team Chromosome Dynamics and Recombination investigates the mechanisms that repair programmed and accidental DNA double‑strand breaks (DSB) to maintain genome stability and are often deregulated in cancers. We combine yeast genetics, mammalian cell culture, proteomic and genomic approaches to decipher the fine molecular mechanisms of homologous recombination during meiosis or somatic growth. We are seeking a motivated Assistant Engineer or Study Engineer in Biology to contribute to a project investigating DSB repair in mammalian cells by advanced genome sequencing, using an innovative way to target DSB at specific sites. The recruited engineer will develop the novel CRISPR editing approach in different wildtype and mutant backgrounds. The Successful Candidate Will Be Responsible For Maintenance of several cell lines. Performing electroporation experiments and molecular assays (including CRISPR technology) to induce double‑strand breaks. Analyzing the outcome of these experiments by imaging and molecular biology such as ChIP‑seq assays and library preparation. Collaborating closely with researchers to analyze experimental data and contribute to the advancement of the project. Candidate Profile Training and Experience Required Education: Bachelor or Master’s degree (MSc) in molecular and cellular biology, biotechnology, or a related field. Experience: At least 2–3 years of hands‑on experience in mammalian cell culture (mandatory). Experience with CRISPR editing is strongly recommended. Solid background in cellular and molecular biology techniques (PCR, RT‑qPCR, library preparation…) Skills Required Good organizational skills, ability to work independently and in a team. Rigor, motivation, and enthusiasm for research. Fluency in English. Contract Information Type of contract: Fixed‑term contract. Starting date: 15/01/2026. Duration: 5 months. Working time: Full time. Remuneration: According to qualification and the current grids. Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance. Location: Paris. Contact: Please send your CV, letter of motivation and 2 references. Publication date: 09/12/2025. Deadline for application: until filled. Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity. #J-18808-Ljbffr


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