Engineer in biology

il y a 1 jour


Paris, France Université PSL Temps plein

About us The hosting structure The Curie Institute Research Center The “Institut Curie” is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Curie Institute Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient. Mission Job description Laboratory Institut Curie, CNRS UMR 3244 – team Valérie Borde : Chromosome Dynamics and Recombination https://institut-curie.org/team/borde Missions Our team Chromosome Dynamics and Recombination investigates the mechanisms that repair programmed and accidental DNA double‑strand breaks (DSB) in order to maintain genome stability and that are often disregulated in cancers. We combine yeast genetics, mammalian cell culture, proteomic and genomic approaches to decipher the fine molecular mechanisms of homologous recombination during meiosis or somatic growth. Our team is seeking a motivated Assistant Engineer (AI) or Study Engineer (IE) in Biology to contribute to a project investigating the study of DSB repair in mammalian cells by advanced genome sequencing, using an innovative way to target DSB at specific sites. For this, the recruited IE will develop the novel CRISPR editing approach that we intend to use in different wildtype and mutant backgrounds. The successful candidate will be responsible for : Maintenance of several cell lines. Performing electroporation experiments and molecular assays (including CRISPR technology) to induce double‑strand breaks. Analyze the outcome of these experiments by imaging and molecular biology such as ChIPseq assays and library preparation. Bioinformatic analyses will be performed with a researcher in the lab. Collaborating closely with researchers to analyze experimental data and contribute to the advancement of the project. Profile Candidate Profile Training and experience required Education : Bachelor or Master’s degree (MSc) in molecular and cellular biology, biotechnology, or a related field. Experience : At least 2-3 years of hands‑on experience in mammalian cell culture (mandatory). Experience with CRISPR editing is strongly recommended. Solid background in cellular and molecular biology techniques (PCR, RT‑qPCR, library preparation…). Skills required Good organizational skills, ability to work both independently and in a team. Rigor, motivation, and enthusiasm for research. Fluency in English All our opportunities are open to people with disabilities Contract information Type of contract : Fixed‑term contract Starting date : 15 / 01 / 2026 Duration : 5 months Working time : full time Remuneration : according to qualification and the current grids Benefits : Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance Location of the position : Paris Contact Please send your CV, letter of motivation and 2 references Publication date : 09 / 12 / 2025 Deadline for application : until filled Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity. https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf #J-18808-Ljbffr


  • Engineer in biology

    il y a 1 jour


    Paris, France Institut Curie Temps plein

    Join to apply for the Engineer in biology (F/M) role at Institut Curie. Institut Curie is a major player in the research and fight against cancer. It consists of a hospital and a Research Center of more than 1000 employees with a strong international representativeness. Missions Our team Chromosome Dynamics and Recombination investigates the mechanisms that...

  • Engineer in biology

    il y a 1 jour


    Paris, France Institut Curie Temps plein

    Job description Institut Curie, CNRS UMR 3244 – team Valérie Borde: Chromosome Dynamics and Recombination Missions Our team Chromosome Dynamics and Recombination investigates the mechanisms that repair programmed and accidental DNA double-strand breaks (DSB) in order to maintain genome stability and that are often disregulated in cancers. We combine yeast...


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