mRNA-LNP Senior Process Development Scientist

mRNA-LNP Senior Process Development Scientist (H/F) The Project mRNA is an extraordinary opportunity to provide vaccines and therapies in a record time and at the right cost and place, especially in countries that have been poorly served up to now. Such a fast-to-develop technology should go with a fast-to-scale manufacturing process, offering highly flexible capacity. Additionally, the Biopharma industry needs to be more sustainable and reduce its carbon footprint. For meeting such requirements, Dillico is developing a continuous, digitized and scale-up-free GMP mRNA manufacturing equipment. This ambitious venture project has strong technical foundations from the co-founders, with experiences in major biopharma players, and from a strong expertise of the R&D team – the project benefits also from strong IP assets. We are working to develop a solution which serves both the biopharma industry and the people, including LMICs, through intensive exchanges and partnerships with key players. Responsibilities Set up scale-down downstream & formulation experiment Define process development strategy – Design & perform associated experiment Compile experimental and analytical results, perform data interpretation, summarize, and report on data with conclusions and recommended next steps Propose improvements and innovative solutions Maintain thorough electronic lab notebooks and documentation records Establish process control strategy Support mRNA drug substance and drug product process development activities for our partners / customers Communicate findings internally and externally through meeting with partners and at conferences Collaborate with the Modeling, Analytical, Process Engineers and Automation people to transfer the developed process units to the GMP‑like pilot Profile and experiences The successful candidate will have significant experience in large-molecule process development (i.e. chromatography, tangential flow, sterile filtration) and/or in mRNA encapsulation development. PhD or Postdoc or experienced R&D scientist (MS) with proven experience in large‑molecule process development, including deep understanding of the chromatography, TFF, sterile filtration and/or mRNA encapsulation 2‑5 years of experience (PhD) or 8‑10 years of experience (MS) in an industrial setting Proven experience in DoE, multivariate analysis and quality‑by‑design Exceptional experimental & analytical skills Innovative mindset, team player who fosters collaboration Strong communication and collaboration skills, and examples of leadership in process development. Knowledge in scale‑down model development and process characterization. Ability to manage multiple projects in a fast‑paced environment and experience managing direct reports Proactive, eager to learn, agile and curious about startup and deeptech environments Very good level of professional English required, Fluent level of French is a plus. What we offer A unique opportunity to take part of the development of a start-up where your contribution will be key to the success of the project. You will be able to grow your career by working in a state‑of‑the‑art innovative environment where you will explore and innovate while working with diverse clients, teams, academic and leaders in the field. You will be empowered to take important technical and business decisions while working with a great team of experts. Attractive work conditions: Stimulating work environment: multicultural and motivated team Live and work close to the Alps Lunch vouchers 50% of local transportation costs paid 5 weeks of holidays per year + 2 weeks of compensation time (RTT) Industry‑leading healthcare Opportunities to network and connect with worldwide experts (clusters) Position located in Grenoble area, France, one of the major high‑tech hubs in Europe Send your application including CV at hr@dillico.com #J-18808-Ljbffr