Head of Computational Drug Design

il y a 14 heures


Paris, France BioTalent Ltd Temps plein

We are seeking a Head of Computational Drug Design to lead and scale our computational capabilities across protein engineering, structural biology, and AI-driven drug discovery. This is a senior leadership role within the Protein & Vector Engineering function, with responsibility for defining computational strategy, driving scientific excellence, and enabling high-impact biologics, chemistry, and genomics programmes. You will work closely with senior scientific leadership and cross-functional teams to deliver innovative computational solutions across the drug discovery pipeline. What this role offers Strategic ownership of computational drug design across multiple therapeutic programmes Leadership of AI- and computation-driven drug discovery initiatives A highly collaborative, multidisciplinary environment (protein engineering, genomics, data science) Opportunity to shape platform development and contribute to publications, patents, and long-term strategy Key responsibilities Define and lead the computational strategy for drug design, molecular modelling, and structural bioinformatics Drive the design and execution of advanced workflows (MD, QM, protein & antibody design, AI/ML-enabled CDD) Lead, mentor, and develop computational scientists, fostering scientific rigor and innovation Build and scale robust, reproducible in-house computational pipelines and best practices Partner closely with internal teams and external collaborators to advance therapeutic programmes What you’ll bring PhD in computational biology, computational chemistry, structural bioinformatics, or a related field 7+ years’ experience in computational drug design or molecular modelling, including leadership responsibility Deep expertise in structural bioinformatics, computational chemistry, and AI/ML applications Strong programming skills (Python, R, Bash) and experience with modern scientific workflows Hands-on experience with tools such as Schrödinger, MOE, Rosetta, PyMOL, AlphaFold Nice to have Experience with HPC and/or cloud computing environments Peptide modelling expertise Broad exposure to end-to-end drug discovery programmes #J-18808-Ljbffr



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