Engineer in Homologous Recombination
il y a 18 heures
About the Institute Institut Curie Research Center is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis, prognosis, and therapeutics of cancers as part of the continuum between basic research and innovation serving the patient. Mission The laboratory The successful candidate will join the Compartmentalization and Dynamics of Nuclear Functions team led by Angela Taddei at Institut Curie (https://curie.fr/equipe/taddei). Our research focuses on understanding how nuclear organization regulates genome functions, with a particular emphasis on homologous recombination. We combine state-of-the-art in vivo quantitative microscopy approaches, including super-resolution imaging, with genetic and molecular biology techniques. The project This position is part of a newly funded technology transfer project aimed at identifying novel inhibitors of homologous recombination. The candidate will be actively involved in all phases of the project, from the establishment of the laboratory pilot assay to the execution of a large-scale screen at the BioPhenics high-content imaging platform, followed by validation of candidate hits. This project offers a unique opportunity to work at the interface of fundamental research, advanced imaging, and translational science. Profile Education and competences Master’s degree in Molecular and Cellular Biology or Engineering degree Fluency in English is required, as English is the working language of the laboratory Expectations / Role Responsibilities The candidate is expected to contribute actively to the development, execution, and analysis of a high-content screening strategy. Responsibilities will include: Performing cell culture experiments using human cell lines, including inhibitor treatments and transfections with siRNA and plasmids Conducting molecular biology experiments, including cloning Developing and optimizing the screening pipeline in close collaboration with the BioPhenics platform, encompassing both technical implementation and data analysis Validating candidate targets using cellular assays such as homologous recombination assays, focus formation assays, and cytotoxicity assays Skills And Profile Background or hands-on experience in cell culture, molecular biology, and/or image analysis is advantageous but not mandatory Strong motivation to learn interdisciplinary techniques and work in a collaborative environment Contract information Type of contract: Fixed-term contract Starting date: Position available immediately Duration: 12 months Working time: full time Remuneration: according to the current grids Benefits: Collective catering, reimbursement of transportation fees up to 70%, supplementary health insurance Location of the position: Paris Contact Please send your CV and letter of motivation to Publication date: 15/01/2026 Deadline for application: until filled Institut Curie is an inclusive, equal opportunity employer and is dedicated to the highest standards of research integrity https://euraxess.ec.europa.eu/sites/default/files/brochures/eur_21620_en-fr.pdf Référence de l'offre : dewv6uk59o #J-18808-Ljbffr
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Engineer in Homologous Recombination
il y a 2 semaines
Paris, Île-de-France Institut Curie Temps pleinAbout UsInstitut Curie Research Centeris a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis,...
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Engineer in Homologous Recombination
il y a 14 heures
Paris, France PSL Research University Temps pleinOverviewInstitute Curie Research Center is a major player in the research and fight against cancer. It consists of a Hospital group and a Research Center of more than 1000 employees with a strong international representativeness. The objective of the Research Center is to develop basic research and to use the knowledge produced to improve the diagnosis,...
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Homologous Recombination Imaging
il y a 15 heures
Paris, France Institut Curie Temps pleinA leading cancer research institute in Paris is seeking a Research Scientist to join their team focusing on homologous recombination. The successful candidate will contribute to developing a screening strategy and perform cell culture and molecular biology experiments. Ideal candidates hold a Master’s degree and have a motivation to learn and collaborate....
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Research Scientist: Homologous Recombination
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Paris, France PSL Research University Temps pleinUn centre de recherche en médecine basé à Paris recherche un(e) candidat(e) pour un projet de recherche sur l'inhibition de la recombinaison homologique. Ce poste à durée déterminée de 12 mois nécessite un Master en biologie moléculaire et une bonne maîtrise de l'anglais. Les responsabilités incluent la culture cellulaire, l'utilisation d'outils...
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