Thesis position – Respiratory deficits in the Congenital Central Hypoventilation Syndrome
il y a 22 heures
Thesis position – Respiratory deficits in the Congenital Central Hypoventilation Syndrome (CCHS): underlying central mechanisms and therapeutic treatments.Congenital Central Hypoventilation Syndrome (CCHS) is a human disease caused by the mutation of Phox2b, a gene coding for a transcription factor involved in the specification of the autonome system, including groups of neurons required for proper breathing behavior. This mutation results at birth in a severe hypoventilation, which develops up to lethal apneas during sleep and a lack of central chemosensibility (no response to a high level of CO2). Human babies cannot survive unless being mechanically supported for breathing. Animal models recapitulating the most common human mutations have been developed and are currently used to investigate the central mechanisms underlying the observed respiratory deficits and more importantly to search for molecules potentially efficient in compensating central anomalies in the control of breathing. The aim of the proposed PhD program is to continue investigating central bases for respiratory deficits associated with CCHS, deciphering the role of microglia and to test one or two molecules with potential clinical relevance that could be used to alleviate the depressed respiration in mutant animals.To achieve this goal, electrophysiological recordings of neuronal activities generated by central respiratory networks will be associated with calcium imaging on in vitro preparations and with pharmaceutical treatments to alleviate respiratory deficits on animal models for CCHS. Immunohistochemical approaches will also be performed on isolated brainstem tissue and in association with tissue transparization (Clarity method).Knowledge in electrophysiology and neural networks would be appreciated.• neural network• rhythmogenesis• mouse• membrane properties• breathingYou want to apply?Please send a cover letter and a CV to :Muriel Thoby-Brissonmuriel.thoby-brisson@u-bordeaux.frPublication: 12/05/25Last update 12/05/25 #J-18808-Ljbffr
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Bordeaux, France Bordeaux Neurocampus Temps pleinPost-doctoral position – Microglia and respiratory dysfunction in CCHS (or Ondine syndrome).The team “Development and Neurobiology of Neural Networks” (DN3) headed by Muriel Thoby-Brisson and Grégory Barrière at Institut des Neurosciences Cognitives et Intégratives d’Aquitaine (INCIA) in Bordeaux is seeking one talented, enthusiastic and...
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Bordeaux, France Bordeaux Neurocampus Temps pleinPostdoc position in Cellular Molecular Neuroscience – Synaptic plasticity mechanismsLocation : Interdisciplinary Institute for Neuroscience, Bordeaux, FranceOur team: The MAP team at the Interdisciplinary Institute for Neuroscience (IINS) is seeking motivated and independent postdoctoral researchers to investigate the molecular and cellular mechanisms...
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Two post doctoral positions in Systems Neuroscience
il y a 19 heures
Bordeaux, France Bordeaux Neurocampus Temps pleinTwo post doctoral positions in Systems NeuroscienceThe Takahashi lab at the Interdisciplinary Institute for Neuroscience (IINS – UMR 5927), part of the Bordeaux Neurocampus, is seeking two postdocs. Our lab, “Neural Basis of Perception,” investigates how cortical circuits process somatosensory information to shape tactile perception in mice...
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Post doctoral position in neurometabolism
il y a 21 heures
Bordeaux, France Bordeaux Neurocampus Temps pleinWe are seeking a highly motivated junior postdoctoral researcher to join the Energy Balance and Obesity research laboratory (http://www.neurocentre-magendie.fr/cota ) at the INSERM U1215, Neurocentre Magendie in Bordeaux, France.The research focus of the team is the study of the neurobiology of obesity and diabetes. The current project aims to shed light on...
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Group leader tenure-track position in Computational Neuroscience
il y a 23 heures
Bordeaux, France Bordeaux Neurocampus Temps pleinGroup leader tenure-track positionin Computational NeuroscienceDescription:The Neurocenter Magendie is a behavioral neuroscience institute including 11 teams dedicated to the study of brain functions in health and disease. We are seeking a high profile, dynamic and innovative researcher to integrate our community. The ideal candidate will possess deep...
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France – PhD in Marketing
il y a 23 heures
Bordeaux, France PhDFinder Temps pleinFrance – PhD in Marketing & New Consumption at KEDGE Business School Be among the first 25 applicants. University: KEDGE Business School Country: France Deadline: 2026-02-01 Fields: Marketing, Management Studies, Economics, International Business, Supply Chain Management Are you passionate about advancing your expertise in marketing, management, or...
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Postdoc position in Cellular
il y a 24 heures
Bordeaux, France Unist Temps pleinNeurosciences » Neurophysiology Organisation/Company CNRS - University of Bordeaux Department Interdisciplinary Institute for Neuroscience Research Field Neurosciences » Neurophysiology Researcher Profile Recognised Researcher (R2) Positions Postdoc Positions Country France Application Deadline 1 Feb 2026 - 00:00 (Europe/Paris) Type of Contract Temporary...
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Post Doctoral Position
il y a 22 heures
Bordeaux, France France Life Imaging Temps pleinType de structure : The Neurofunctional Imaging Group (GIN) is a CNRS-CEA joint research unit of the Bordeaux University (UMR 5296, dir. Bernard Mazoyer) and a core member of the TRAIL Laboratory of Excellence. The GIN is a multidisciplinary research unit gathering scientists with initial training in mathematics and instrumentation, cognitive neurosciences,...
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Post doc position – Body/brain relationship in drug addiction
il y a 20 heures
Bordeaux, France Bordeaux Neurocampus Temps pleinAimsThe project, in collaboration with JR Cazalets from the Motopsyn team, aims to understand the relationship between the body and brain in drug addiction. Specifically, it will investigate the role of peripheral signals (such as temperature, heart rate, blood pressure, and respiration), produced by cocaine and nicotine, in influencing the propensity to...
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Junior Professor Position – Molecular and Cellular Neurosciences
il y a 21 heures
Bordeaux, France Bordeaux Neurocampus Temps pleinJunior Professor Position – Molecular and Cellular Neurosciences The University of Bordeaux opens a Junior Professorship in Neuroscience. The position is part of the University research strategy that is structured around “Grands Programmes de Recherche” such as the GPR BRAIN_2030. The Bordeaux Neurocampus is made up of 800 international scientists who...
