Postdoctoral Researcher

Il y a 2 mois


Palaiseau, Île-de-France INRIA Temps plein

About INRIA

INRIA is a leading French research institute in computer science, control, and applied mathematics, promoting scientific excellence and technology transfer.

Research Group

The research group focuses on the intersection of mathematical biology, statistics, control engineering, and statistical physics applied to problems in biology.

Job Mission

The objective of this project is to develop and program sensitivity estimation methods for continuous-time Markov chain models of biochemical reactions inside cells that are coupled to the dynamics of growing populations.

Main Activities

  • Develop sensitivity estimation methods for multi-scale stochastic models based on the Girsanov measure transformation and finite difference methods.
  • Test methods on several toy examples.
  • Analyze microscopy data of collaborators.
  • Construct a stochastic model of a repressilator gene circuit using microscopy data.
  • Apply sensitivity estimation methods to this model.

Required Skills

  • Strong programming skills.
  • Prior experience with single-cell microscopy data.
  • Prior experience with continuous-time Markov chain models of chemical reactions.
  • Prior experience with sensitivity analysis.

Benefits

  • Subsidized meals.
  • Partial reimbursement of public transport costs.
  • Leave: 7 weeks of annual leave + 10 extra days off due to RTT (statutory reduction in working hours) + possibility of exceptional leave.
  • Possibility of teleworking and flexible organization of working hours.
  • Professional equipment available.
  • Social, cultural, and sports events and activities.
  • Access to vocational training.
  • Social security coverage.


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