Postdoctoral Research Scientist

il y a 8 heures

Paris, Île-de-France Imagine - Institut des maladies génétiques Temps plein
About Us

The Imagine Institute is a leading research center focused on understanding genetic diseases that affect the immune system, skeletal dysplasia, nervous system, and other areas. Our team of experts is dedicated to translating research findings into clinical applications, with a strong emphasis on patient-driven research.

We are seeking a highly motivated postdoctoral researcher to join our team and contribute to our research projects investigating mechanisms of epilepsy, particularly Developmental Epileptic Encephalopathies (DEEs). The successful candidate will have the opportunity to work with our team of experts in a collaborative and dynamic environment.

Project Overview

The main goal of this project is to investigate the physiopathological mechanisms of discovered potassium channel mutations in DEEs using in vitro and in vivo models. The candidate will have the opportunity to explore a range of scientific questions using zebrafish genetic models, patient cell lines, and organoids, with the goal of taking novel genetic discoveries from the mechanistic investigation to therapeutic leads.

Key Responsibilities
  • Conduct research projects investigating mechanisms of epilepsy, particularly DEEs
  • Develop and implement in vitro and in vivo models to study potassium channel mutations
  • Collaborate with our team of experts to design and execute experiments
  • Analyze and interpret data to identify novel therapeutic targets
  • Communicate research findings through publications and presentations
Requirements
  • PhD in molecular biology, genetics, neuroscience, or related areas
  • Good publication track record
  • Experimental skills in hiPSC culture are a plus
  • Additional skills in epilepsy, animal experimentation (zebrafish), and cell imaging are considered a plus
  • Team player attitude and problem-solving skills
  • Self-motivation and ability to work independently
What We Offer
  • Fixed-term contract: 2 years, renewable
  • During this period, the successful candidate will be encouraged to apply for an external postdoctoral fellowship to pursue the project
  • Starting date: flexible
  • Salary: on experience
How to Apply

Please send a motivation letter with a statement of research interest, a detailed CV with publication list, and three references.

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