Postdoctoral Research Scientist

il y a 2 semaines


Paris, Île-de-France Imagine - Institut des maladies génétiques Temps plein
About Us

The Imagine Institute is a leading research center focused on understanding genetic diseases that affect the immune system, skeletal dysplasia, nervous system, and other areas. Our team is dedicated to translating research findings into clinical applications, with a strong emphasis on patient-driven research.

We are seeking a highly motivated postdoctoral researcher to join our team and contribute to our research projects investigating mechanisms of epilepsy, particularly Developmental Epileptic Encephalopathies (DEEs). The successful candidate will work closely with our team of experts in molecular biology, genetics, and neuroscience to develop innovative approaches to understanding and treating epilepsy.

Project Overview

The Innov4-ePik project is a collaborative effort between academic and industrial partners to develop new therapeutic approaches for patients with drug-resistant epilepsy. Our team will focus on investigating the physiopathological mechanisms of discovered potassium channel mutations in DEEs using in vitro and in vivo models.

The candidate will have the opportunity to explore a range of scientific questions using zebrafish genetic models, patient cell lines, and organoids, with the goal of taking novel genetic discoveries from the mechanistic investigation to therapeutic leads. Our close collaboration with expert technological platforms allows access to the latest tools for fundamental research, biomarker identification, and development of automated drug screening assays.

Requirements
  • PhD in molecular biology, genetics, neuroscience, or related areas
  • Good publication track record
  • Experimental skills in hiPSC culture are a plus
  • Additional skills in epilepsy, animal experimentation (zebrafish), and cell imaging are considered a plus
  • Team player attitude and problem-solving skills
  • Self-motivation and ability to work independently

(Knowledge of French is not a requirement.)

Contract
  • Fixed-term contract: 2 years, renewable
  • During this period, the successful candidate will be encouraged to apply for an external postdoctoral fellowship to pursue the project
  • Starting date: flexible
  • Salary: on experience
Application

Please send a motivation letter with a statement of research interest, a detailed CV with publication list, and three references.



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