Biological Evaluation of Radiotracers for PET Imaging of Mutated Isocitrate Dehydrogenases

il y a 1 semaine


Lyon, Auvergne-Rhône-Alpes, France Imagerie Moléculaire et Stratégies Théranostiques UMR 1240, INSERM, UCA Temps plein
Job Description

We are seeking a highly motivated Postdoctoral Researcher to join our team at Imagerie Moléculaire et Stratégies Théranostiques UMR 1240, INSERM, UCA. The successful candidate will be responsible for the biological evaluation of innovative radiotracers targeting mIDH1 for PET and SPECT imaging.

Key Responsibilities:
  • In vitro evaluation of new radioiodinated and radiofluorinated mIDH1 ligands on cultured tumor cells
  • Characterization of preclinical animal models of solid tumors
  • In vivo biodistribution studies by SPECT or PET imaging and ex vivo gamma-counting of promising radiotracers
Requirements:
  • Ph.D. degree or equivalent in biology or biomedical sciences
  • Strong background and PhD training in cancer biology, molecular biology, or biochemistry
  • Experience in biological assays, including cell culturing, Western Blotting, immunohistochemistry, and statistical analyses
  • Knowledge of handling radioactive material
  • Experience with in vitro characterization of radiotracers (uptake, competition assay)
  • Experience with tumor imaging or preclinical disease models for molecular imaging procedures
  • Willingness to work with animals (mice handling, intravenous injection, tissue processing) and authorization to conduct experiments on animals - Level 1 or 2
  • Strong commitment to experimental bench research
  • Collaborative and self-motivated style necessary for effective teamwork
  • Excellent communication and writing skills in English and/or French
About the Project:

The aim of this post-doc position is the biological evaluation of innovative radiotracers targeting mIDH1 for PET and SPECT imaging. The candidate will be responsible for the in vitro evaluation of new radioiodinated and radiofluorinated mIDH1 ligands on cultured tumor cells, characterization of preclinical animal models of solid tumors, and in vivo biodistribution studies by SPECT or PET imaging and ex vivo gamma-counting of promising radiotracers.

This international project will be performed in collaboration with the neuroradiopharmacy laboratory of the HZDR (Research site Leipzig, Germany).



  • Lyon, Auvergne-Rhône-Alpes, France France Life Imaging Temps plein

    Job DescriptionWe are seeking a highly motivated Postdoctoral Researcher to join our team at France Life Imaging. The successful candidate will work on the development of a 3D platform for Passive Acoustic Mapping of cavitation.Project OverviewThe CAVIIAR ANR Project is a collaborative effort between the Laboratory of Therapeutic Applications of Ultrasound...


  • Lyon, Auvergne-Rhône-Alpes, France France Life Imaging Temps plein

    Job Title: Postdoctoral Researcher in Acoustic Mapping of CavitationJob Description:Job Context:The CAVIIAR ANR Project is a collaborative research project between the Laboratory of Therapeutic Applications of Ultrasound (LabTAU) and the Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS). The candidate will work with...

  • Postdoctoral Researcher

    il y a 4 semaines


    Lyon, Auvergne-Rhône-Alpes, France CNRS Temps plein

    Job SummaryThe CNRS is seeking a postdoctoral researcher to work on the development of ion computed tomography techniques, specifically the sandwich time-of-flight method. The successful candidate will be responsible for developing simulations, modeling inverse problems, and implementing algorithms for image reconstruction.Key ResponsibilitiesDevelop a...


  • Lyon, Auvergne-Rhône-Alpes, France Centre national de la recherche scientifique Temps plein

    Project OverviewThe Centre national de la recherche scientifique is seeking a highly motivated Master 2 student or equivalent to join our "Regeneration of OsteoArticular and Dental tissues" (ROAD) team within the LBTI (Laboratory for Tissue Biology and Therapeutic Engineering). Our laboratory is part of the IBCP research institute and located on the Gerland...


  • Lyon, Auvergne-Rhône-Alpes, France Celebree School of Thorndale Temps plein

    Job DescriptionYou will lead the local submission management process, from planning to finalizing local submissions, and develop a Health Authority engagement strategy. As the point of contact for local Health Authorities, you will serve as the representative in the local industry association.In this role, you will develop country product plans based on...


  • Lyon, Auvergne-Rhône-Alpes, France France Life Imaging Temps plein

    Job Title:Postdoctoral Position on Development of a 3D Platform for Passive Acoustic Mapping of CavitationAbout the Project:The CAVIIAR ANR Project is a collaborative effort between the Laboratory of Therapeutic Applications of Ultrasound (LabTAU) and the Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé (CREATIS). This project...


  • Lyon, Auvergne-Rhône-Alpes, France Celebree School of Thorndale Temps plein

    Job SummaryWe are seeking a highly skilled and experienced Regulatory Affairs Specialist to lead our local submission management from planning to finalizing local submissions and define the Health Authority (HA) engagement strategy. As the point of contact for local Health Authorities, you will serve as the representative in the local industry...


  • Lyon, Auvergne-Rhône-Alpes, France Afppe Temps plein

    Job Title: Radiology TechnicianCompany: AfppeWe are seeking a skilled Radiology Imaging Specialist to join our medical team at Afppe.The ideal candidate will have a passion for X-ray imaging and a strong desire to work in a dynamic medical environment.We offer a state-of-the-art technology platform, including MRI, CT Scanner, and Angio CT, to support our...


  • Lyon, Auvergne-Rhône-Alpes, France Celebree School of Thorndale Temps plein

    Job SummaryWe are seeking a highly skilled Head of Regulatory Affairs France to lead our local submission management team and develop country product plans based on global/regional strategy and business plans.Key ResponsibilitiesLead local submission management from planning to finalizing local submissions and define the Health Authority (HA) engagement...

  • Electronics Engineer

    il y a 1 semaine


    Lyon, Auvergne-Rhône-Alpes, France HawkCell Ltd Temps plein

    HawkCell Ltd is a leading company in animal imaging, and we are seeking a talented Electronics Engineer to join our team. As an Electronics Engineer, you will work on assembling, testing, and maintaining our electronic boards, ensuring high performance and reliability of our products.The ideal candidate will have experience in analog electronics, assembly,...


  • Lyon, Auvergne-Rhône-Alpes, France Afppe Temps plein

    **Job Summary**Afppe is seeking a highly skilled Medical Imaging Research Technician to join our team in a cutting-edge European research project. As a key member of our team, you will be responsible for performing quantitative and qualitative analysis of medical images (primarily MRI/CT thoracic scans), reviewing and annotating images, tracking studies,...

  • Director of Product Strategy

    il y a 2 semaines


    Lyon, Auvergne-Rhône-Alpes, France Edmund Optics India Private Limited Temps plein

    Product Line Manager - Strategic OpticsEdmund Optics is seeking a highly skilled and experienced Product Line Manager to lead our Strategic Optics product line. As a key member of our team, you will be responsible for developing and executing a product strategy that aligns with our company's technological vision and core competencies.Key...


  • Lyon, Auvergne-Rhône-Alpes, France Thermo Fisher Scientific Temps plein

    Work Schedule and EnvironmentStandard (Monday to Friday) office hours.Job OverviewAs a Technical Sales Specialist for Imaging and Detection, you will play a key role in promoting and selling microscopes, high-content analysis instruments, and multimode plate readers in France and emerging markets.Key ResponsibilitiesDevelop and implement an effective...


  • Lyon, Auvergne-Rhône-Alpes, France Thermo Fisher Scientific Temps plein

    Work Schedule and EnvironmentStandard working hours, Monday to Friday, in a comfortable office environment.Job OverviewAs a Technical Sales Specialist for Imaging and Detection, you will be part of a dynamic team at Thermo Fisher Scientific Inc. that is dedicated to delivering innovative products and services. Your primary responsibility will be to promote...

  • Director of Agency

    Il y a 2 mois


    Lyon, Auvergne-Rhône-Alpes, France Accile Temps plein

    **About Accile**Accile is a fast-growing ESN (Enterprise Software Solutions) company with a strong presence in the French market. With a revenue of 6 million euros and 120 employees, we are expanding our operations to the Lyon region and seeking a highly skilled professional to lead our agency.**Job Summary**We are looking for a seasoned sales professional...

  • Chargé d'évaluation

    il y a 3 semaines


    Lyon, Auvergne-Rhône-Alpes, France l'association Forum réfugiés Temps plein

    About the RoleWe are seeking a highly skilled and compassionate Chargé d'évaluation to join our team at l'association Forum réfugiés. As a key member of our staff, you will play a vital role in conducting and coordinating multidisciplinary evaluations of young people in need.Key ResponsibilitiesConduct thorough evaluations of young people, taking...


  • Lyon, Auvergne-Rhône-Alpes, France MICHAEL PAGE Temps plein

    About the RoleWe are seeking a highly experienced and skilled Director of Consolidation to join our team at Michael Page. As a key member of our financial services team, you will be responsible for leading our consolidation services and driving business growth.Key ResponsibilitiesLead and manage a team of consolidation professionals to deliver high-quality...

  • Radiology Technician

    il y a 3 semaines


    Lyon, Auvergne-Rhône-Alpes, France Afppe Temps plein

    Explore the Inner Workings of the Human BodyAre you fascinated by the world of medical imaging and the thrill of discovery that comes with it? Do you have a passion for working with cutting-edge technology and a team of dedicated professionals?About the RoleWe are seeking a skilled and motivated individual to join our radiology team at Afppe. As a radiology...

  • Research Scientist

    il y a 2 semaines


    Lyon, Auvergne-Rhône-Alpes, France LAGEP - Université de Lyon Temps plein

    Develop a Novel W-Based Contrast Agent for Lung Pathology ImagingAs a research scientist at LAGEPP, you will work on formulating a new contrast agent for Spectral Photon Counting Scanner (SPCCT) imaging. This project aims to develop a high-sensitivity contrast agent composed of tungsten (W) for imaging lung pathologies. Your task will involve working with a...


  • Lyon, Auvergne-Rhône-Alpes, France UCLy Temps plein

    UCLy's Faculty of Law in Lyon is actively seeking accomplished legal professionals to join our esteemed institution.We invite applications from individuals with a demonstrated commitment to teaching and research excellence within the dynamic field of law.Areas of SpecializationCivil LawBusiness Law (Domestic and International)Comparative Law (Comparative...