Biophysics Researcher

il y a 2 jours


Grenoble, Auvergne-Rhône-Alpes, France ESRF Temps plein

Context & Job Description

The ESRF is seeking a highly motivated PhD student to investigate phase separating proteins using a combination of X-ray photon correlation spectroscopy and small angle X-ray scattering.

Phase separations are revolutionizing biology, but the underlying physics is poorly understood. This project aims to develop new methodologies to probe PS formation, dynamics, structure, and to develop predictive models governing its behavior.

The proposed thesis project will use the protein EARLY FLOWERING 3 (ELF3) from Arabidopsis thaliana as a model. Recombinant ELF3 in the soluble, liquid condensed, and hydrogel phases will be studied using XPCS and SAXS to determine structural and dynamic properties in the different phases.

The project will be in collaboration between ESRF and the Cell & Plant Physiology Laboratory in Grenoble. It will require studying a wide breadth of different techniques, including biophysical and structural methods. This will provide the student with extensive mobility opportunities and the chance to work with global experts.

Expected Profile

  • PhD in Physics, Biophysics, Biology, or a related field
  • Proficiency in Python or similar programming languages
  • Self-motivated and self-driven
  • A strong general interest in Biophysics
  • Proficiency in English (working language at the ESRF)

Working Conditions

The salary will be calculated on the basis of relevant qualifications and professional experience. The ESRF offers a competitive compensation and allowances package, including financial support for relocation to Grenoble.


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