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Synthetic and Systems Biology Researcher

Il y a 2 mois


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Job Description

About the Role:

We are seeking a highly motivated scientist to join our Synthetic and Systems Biology team at Lesaffre. As a key member of our team, you will be responsible for developing and optimizing genome engineering tools and technologies to enhance the utility and power of our BUILD and NGS workflow portfolio.

Key Responsibilities:

  • Develop genome engineering tools and technologies: Increase scope, efficiency, and speed of our BUILD workflows by onboard host organisms beyond S. cerevisiae and E. coli, increase efficiency of markerless DNA delivery to industrial strains, unlock multi-locus and multi-gene delivery.
  • Develop custom NGS tools and technologies: Increase the scope, efficiency, and speed of our NGS workflows by custom indexing in library preparation for highly multiplexed DNA sequencing, onboard methods for marker-assisted breeding, onboard methods supporting our protein engineering activities.
  • Contribute to the continuous BUILD and NGS activity: Execute established, highly automated workflows on robotic workcells (maximum 15% of the time) and provide feedback for continuous workflow improvement.
  • Nurture relationships with Recombia teams: Foster collaboration with a focus on genome engineering technologies and associated NGS technology.
  • Stay up-to-date with industry developments: Maintain state-of-the-art knowledge in the area of microbial synthetic and systems biology as well as multiplex custom NGS methods by critically reading papers and participating in relevant conferences.

Requirements:

  • PhD in a microbiology / synthetic biology / systems biology / molecular biology.
  • Experience in custom NGS methods and microbial genome engineering.
  • Ability to analyze your own data with custom scripts.
  • Fluency in English.
  • LIMS experience (Benchling or others) is a plus.

About Lesaffre:

  • We are a successful family-owned company with a long-standing history where people truly matter.
  • We promote a sense of fulfillment with a genuine mission: nourish and protect the planet.
  • An opportunity to work in a real international environment.