Postdoctoral Research Scientist
il y a 4 semaines
The Imagine Institute is a research structure located within Necker Children's Hospital in Paris. Our research labs focus on understanding genetic diseases affecting the immune system, skeletal dysplasia, nervous system, and more.
We are involved in translational research, from patient characterization to modelling and fundamental research. Our goal is to identify therapeutic targets and develop clinical trials.
Our team collaborates with national and international partners to foster research and development of novel treatments.
MissionWe are recruiting a postdoctoral scientist to investigate mechanisms of epilepsy, focusing on Developmental Epileptic Encephalopathies (DEEs).
The selected candidate will contribute to the Innov4-ePik RHU project, funded by the National Research Agency. This project aims to propose a new therapeutic paradigm for patients with drug-resistant epilepsy.
Context :Epilepsies are a group of heterogeneous diseases with seizures onset and co-morbidities. Epilepsies affect around 1% of the population, with a higher incidence in infants and children.
In addition to medical, social, psychological, and economic burden, epilepsies in childhood have a major impact on neurodevelopment and autonomy in adulthood.
Project :The main goal of this project is to investigate the physiopathological mechanisms of discovered potassium channel mutations in DEEs using in vitro and in vivo models.
The candidate will explore scientific questions using zebrafish genetic models, patient cell lines, and organoids. Our collaboration with expert technological platforms allows access to the latest tools for fundamental research and biomarker identification.
Profile- Highly motivated PhD in molecular biology, genetics, neuroscience, or related areas.
- Good publication track record.
- Experimental skills in hiPSC culture are appreciated.
- Additional skills in epilepsy, animal experimentation, and cell imaging are considered a plus.
- Team player attitude and problem-solving skills.
- Self-motivation and ability to work independently.
(Knowledge of French is not a requirement.)
Contract- Fixed-term contract: 2 years, renewable.
- During this period, the successful candidate will be encouraged to apply for an external postdoctoral fellowship.
- Starting date: flexible.
- Salary: on experience.
Please send a motivation letter with a statement of research interest, a detailed CV with publication list, and three references.
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Postdoctoral Research Scientist
il y a 4 semaines
Paris, Île-de-France Imagine - Institut des maladies génétiques Temps pleinAbout the Imagine InstituteThe Imagine Institute is a research structure located within Necker Children's Hospital in Paris. Our research labs focus on understanding the molecular mechanisms of genetic diseases affecting the immune system, skeletal dysplasia, nervous system, stem cell differentiation, kidney physiology, and metabolism.We are seeking a highly...
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Postdoctoral Scientist in Epilepsy Research
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Paris, Île-de-France Imagine - Institut des maladies génétiques Temps pleinAbout Our ResearchThe Imagine Institute is a cutting-edge research structure focused on understanding the molecular mechanisms of genetic diseases affecting the immune system, skeletal dysplasia, nervous system, and more. Our team is committed to translational research, from patient characterization to therapeutic targets and clinical trials. We employ a...
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