Neurobiologist Researcher in Cellular Epilepsy
il y a 2 semaines
This PhD thesis is integrated within the framework of the ERANET-NEURON funded project AUTONOMIC and of the ERC funded project EPIAROUSAL. Both seizures and their complications are modulated by patients' vigilance states. Several epilepsy complications are associated with sleep, including Sudden and Unexpected Death in Epilepsy (SUDEP). SUDEP primarily results from a fatal postictal central apnea after a nocturnal generalized convulsive seizures.
Reducing the severity of postictal respiratory dysfunction has thus appeared as one of the most promising ways to prevent SUDEP. However, no encouraging result has been reported yet, suggesting that epilepsy-related respiratory dysfunction may only be the tip of the iceberg. Given the numerous interconnections between the network that regulates arousal and sleep and the respiratory network, one might make the hypothesis that some patients with drug-resistant epilepsy might combine this well-known seizure-related respiratory dysfunction with a chronic alteration of arousal regulation, resulting in abnormal asphyxia-induced arousal.
The project will thus study the interplay between epilepsy-related respiratory dysfunction and arousal regulation.
The project will be conducted in two rodent models of epilepsy: (i) Scn1aRH/+ mice, a mouse model of Dravet Syndrome, a severe neurodevelopmental disease, characterized by infancy onset, severe cognitive deficit and drug-resistant seizures, and high risk of seizure-related death; (ii) rat model of temporal lobe epilepsy (TLE).
The work will use complementary techniques, including long-term cardio-respiratory recordings combined with EEG, in vivo multiunit recordings as well as molecular neurobiology (RT-qPCR and RNAscope).
Administrative organization
- Doctoral school : Neurosciences and Cognition (ED476): https://nsco.universite-lyon.fr/site-francais/
- Funder and Employer : Lyon 1 University. 3-year contract. Salary : 1687 € / month
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PhD Researcher in Cellular Neurobiology and Epilepsy
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinProject OverviewThis PhD thesis is part of the ERANET-NEURON funded project AUTONOMIC and the ERC funded project EPIAROUSAL. The project aims to study the interplay between epilepsy-related respiratory dysfunction and arousal regulation.The research will be conducted in two rodent models of epilepsy: Scn1aRH/+ mice and a rat model of temporal lobe epilepsy....
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PhD Researcher in Cellular Neurobiology and Epilepsy
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinProject Overview We are seeking a highly motivated PhD researcher to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will be working on a project focused on understanding the mechanisms of epilepsy-related respiratory dysfunction and arousal regulation. Research Objectives The PhD project will investigate...
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3-Year PhD Thesis in Human Physiology Researcher
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinResearch Opportunity: We are seeking a highly motivated PhD researcher to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will have the opportunity to work on a 3-year PhD thesis project in human physiology, focusing on epilepsy and sleep medicine.Project Overview: The PhD project will investigate the...
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3-Year PhD Thesis in Human Physiology Researcher
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinJob Title: 3-Year PhD Thesis in Human Physiology Researcher Job Description:Researcher in Human Physiology and Epilepsy At the Centre de Recherche en Neurosciences de Lyon - CRNL, we are seeking a highly motivated PhD Researcher to join our team in the field of Human Physiology and Epilepsy. This 3-year PhD thesis will be integrated within the framework of...
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3 Years PhD Thesis in Human Physiology Researcher
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinJob Title: PhD Researcher in Human Physiology and EpilepsyAbout the Project:We are seeking a highly motivated PhD researcher to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will be working on a 3-year project focused on the interplay between epilepsy-related respiratory dysfunction, arousal regulation,...
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3 Years PhD Researcher in Human Physiology
il y a 3 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinJob Opportunity: PhD Researcher in Human PhysiologyWe are seeking a highly motivated and skilled PhD Researcher to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will be working on a 3-year ERC funded project focused on the investigation of arousal and respiratory co-dysfunction in drug-resistant...
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3-Year PhD Thesis in Human Physiology Researcher
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinJob Title: 3-Year PhD Thesis in Human Physiology ResearcherJob Description:This PhD thesis is part of the ERC-funded project EPIAROUSAL, led by Pr. Sylvain RHEIMS. The project aims to study the interplay between epilepsy-related respiratory dysfunction, arousal regulation, and the brainstem adenosine pathway.Responsibilities:Investigate the relation between...
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PhD position in Neuroplasticity and Meditation Research
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinPhD position in Neuroplasticity and Meditation Research Join our research team at the Institute of Neuroscience and Psychology as a PhD student to investigate the effects of meditation on the brain's intrinsic connectivity networks. This 3-year position is part of a larger project aiming to characterize the plasticity of the aging brain following meditation...
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PhD Researcher in Meditation and Brain Imaging
il y a 4 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinPhD Researcher in Meditation and Brain ImagingWe are seeking a highly motivated PhD researcher to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will have the opportunity to work on a 3-year-funded position, investigating the impacts of meditation training on the organisation of resting state intrinsic...
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PhD Researcher in Meditation and Brain Imaging
il y a 2 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinJob DescriptionCentre de Recherche en Neurosciences de Lyon - CRNL seeks a highly skilled researcher to investigate the effects of meditation on brain plasticity and aging. As a PhD researcher, you will work on a 3-year project to analyze large brain imaging datasets and develop new methods for characterizing neural networks.Responsibilities:- Analyze...
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PhD Researcher: Investigating the Impacts of Meditation on Brain Aging
il y a 3 semaines
Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinPhD Researcher Position: Investigating the Impacts of Meditation on Brain AgingAs a PhD researcher at Centre de Recherche en Neurosciences de Lyon - CRNL, you will have the opportunity to explore the effects of meditation on brain aging in a three-year-funded position.Project Overview: Our project aims to characterize the plasticity of the aging brain...
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Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinPhD Position in Neuroscience: Investigating the Effects of Meditation on Brain FunctionWe are seeking a highly motivated PhD student to join our research team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will have the opportunity to work on a cutting-edge project investigating the effects of meditation on brain...
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Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinAbout the positionWe are seeking a highly motivated Postdoctoral Researcher to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will have the opportunity to work on a 3-year-funded project investigating the plasticity of the aging brain following meditation training.About the projectThe project aims to...
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Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps pleinPhD Position in Neuroscience: Investigating the Effects of Meditation on Brain FunctionWe are seeking a highly motivated PhD candidate to join our research team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will have the opportunity to work on a cutting-edge project investigating the effects of meditation on brain...
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Postdoctoral Researcher
Il y a 5 mois
Bron, France INSERM U1028 Temps plein**Salary**: 2,900.00€ - 3,500.00€ per month **Education**: - Doctorate (required) **Experience**: - research experience after PhD: 2 years (required) - MRI: 2 years (required) **Language**: - English (required) Work Location: In person
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Assistant-e Administratif-ve en Ressources Humaines
Il y a 5 mois
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il y a 24 heures
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