Screening Scientist

il y a 1 mois


GifsurYvette, Île-de-France Servier Temps plein
Job Title: Screening Scientist

We are seeking a highly skilled Screening Scientist to join our team at Servier. As a key member of our drug discovery projects, you will be responsible for identifying and characterizing bioactive molecules that can serve as starting points for the development of new therapeutic solutions.

Your Responsibilities:
  • Lead early drug discovery activities within therapeutic project teams as a Work-Package leader or Core Team Member.
  • Contribute to the definition of strategic lines of the department and execution of tactics as a member of the Department's leadership team.
  • Lead a screening team and be accountable for its contributions to the advancement of therapeutic projects, as well as responsible for the well-being of collaborators.
  • Establish hit identification and triaging strategies as a screening expert.
  • Selection of assays to identify and characterize bioactive molecules.
  • Work closely with colleagues from other poles of activity to produce and validate molecular and cellular tools needed to develop assays.
  • Assay development, optimization, industrialization, and validation.
  • Work closely with other poles of activity to select hits for progression.
  • Ensure correct writing of assay protocols.
  • Ensure data integrity good practices.

Contribute to innovation by evaluating and implementing new technologies to ensure we are well positioned to generate high-quality, biologically relevant information enabling the best decisions in the path towards pre-clinical candidates within reasonable cost and speed.

Your Profile:
  • PhD in Life Sciences.
  • Skills for biological assay development, screening, and profiling.
  • Expertise in biochemical assay development and mechanistic enzymology.
  • Experience with label-free assay technologies is a plus.
  • Management of projects and people.
  • HTS data mining and visualization expertise is a plus.
  • Fluent in English (C1).
  • Post-doctoral experience in biological research with particular emphasis on the development of methodologies for drug discovery and the execution of screening and profiling campaigns.
  • Familiarity with the main solutions for miniaturization and automation of biological assays for HTS.
  • Good team player, organized, rigorous, creative, efficient, and adaptable.

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