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PhD Thesis in Cellular Neurobiology and Epilepsy

il y a 1 mois


Bron, Auvergne-Rhône-Alpes, France Centre de Recherche en Neurosciences de Lyon - CRNL Temps plein
PhD Thesis in Cellular Neurobiology and Epilepsy

We are seeking a highly motivated PhD student to join our team at the Centre de Recherche en Neurosciences de Lyon - CRNL. The successful candidate will work on a project focused on the interplay between epilepsy-related respiratory dysfunction and arousal regulation.

The project will be conducted in two rodent models of epilepsy: Scn1aRH/+ mice and rat model of temporal lobe epilepsy (TLE). The work will use complementary techniques, including long-term cardio-respiratory recordings combined with EEG, in vivo multiunit recordings, and molecular neurobiology (RT-qPCR and RNAscope).

The PhD student will be part of the Translational Group in Epilepsy Research (TIGER) and will have the opportunity to work with a team of experienced researchers, including Dr. Sylvain RHEIMS, Dr. Laurent BEZIN, Dr. Hayet KOUCHI, and Dr. Jonathon SMITH.

The PhD position is funded by the ERANET-NEURON project AUTONOMIC and the ERC funded project EPIAROUSAL. The successful candidate will receive a 3-year contract with a salary of 1687 € / month.

Project Summary:

The project aims to study the interplay between epilepsy-related respiratory dysfunction and arousal regulation. The successful candidate will contribute to the development of new therapeutic strategies for epilepsy-related respiratory dysfunction.

Administrative Organization:

The PhD student will be enrolled in the Doctoral School of Neurosciences and Cognition (ED476) and will be employed by Lyon 1 University.