Fourier Ptychography for Cell Cultures Imaging

Description du poste

**Domaine**:

- Optique et optronique

**Contrat**:

- Stage

**Intitulé de l'offre**:

- Fourier ptychography for cell cultures imaging H/F

**Sujet de stage**:

- In microscopy, imaging large areas with high resolution has always been challenging. Either we look at small regions with fine details, or we look at large regions with coarse details.

Fourier ptychography (FP) is a computational method for synthesizing raw data into a high-resolution and wide field-of-view image through a combination of synthetic aperture and phase retrieval concepts.

Unlike conventional techniques, which trade resolution against imaging field of view, FP can achieve both simultaneously to produce high-throughput imaging of unstained transparent biological samples.

**Durée du contrat (en mois)**:

- 6 months

**Description de l'offre**:

- As an intern at CEA-Leti, you will have the opportunity to work in a world-renowned research environment. Our teams are made up of passionate and dedicated experts, providing a framework conducive to learning and collaboration. You will have access to cutting-edge equipment and top-notch research resources to carry out your missions.During this internship, you will use an existing microscope setup with coded illumination patterns using LED array to acquire data from cell cultures samples.-
This technique can be eventually applied to the high-throughput screening of differentiating STEM cell culture samples in the scope of personalized cell therapy research.**Moyens / Méthodes / Logiciels**:

- Python
- This internship is intended for **final-year engineering or Master 2 students **with basics knowledge of** Fourier optics and microscopy imaging techniques **as well as moderate capabilities of** coding in Python **or equivalent programming language** for image processing.**

Good communication skills, curiosity and a taste for experimentation are appreciated.**Still have doubts? We offer**:

- The opportunity to work within a world-renowned organization in the field of scientific research,
- A unique environment dedicated to ambitious projects addressing major societal challenges,
- A cutting-edge experience with strong industrial development potential,
- Exceptional experimental resources and high-quality supervision,
- Real career opportunities at the end of your internship,
- A position in the heart of the Grenoble metropolitan area, easily accessible via eco-friendly transportation promoted by the CEA (85% coverage of public transportation costs),
- A recognized work-life balance,
- A company restaurant,
- A diversity and inclusion policy.
- All our positions are open to people with disabilities. The CEA Disability Mission supports you and puts in place the necessary arrangements to meet your specific needs._

Localisation du poste

**Site**:

- Grenoble

**Localisation du poste**:

- France, Auvergne-Rhône-Alpes, Isère (38)

**Ville**:

- Grenoble

**Langues**:

- Anglais (Intermédiaire)

**Diplôme préparé**:

- Bac+5 - Diplôme École d'ingénieurs

**Possibilité de poursuite en thèse**:

- Non

Demandeur

**Disponibilité du poste**:

- 03/02/2025

Informations générales

**Entité de rattachement**:
Le CEA est un acteur majeur de la recherche, au service des citoyens, de l'économie et de l'Etat.

Il apporte des solutions concrètes à leurs besoins dans quatre domaines principaux : transition énergétique, transition numérique, technologies pour la médecine du futur, défense et sécurité sur un socle de recherche fondamentale. Le CEA s'engage depuis plus de 75 ans au service de la souveraineté scientifique, technologique et industrielle de la France et de l'Europe pour un présent et un avenir mieux maîtrisés et plus sûrs.

Implanté au cœur des territoires équipés de très grandes infrastructures de recherche, le CEA dispose d'un large éventail de partenaires académiques et industriels en France, en Europe et à l'international.

Les 20 000 collaboratrices et collaborateurs du CEA partagent trois valeurs fondamentales:

- La conscience des responsabilités
- La coopération
- La curiosité

**Référence **:2024-33579**Description de l'unité**:

- The L4IV Laboratory (Optical instrumentation and data-processing for in-vitro imaging) invites you to join a creative, dynamic and passionate team, to take part in great technical challenges.

By joining us, you will contribute to the development of the medical devices that will be used in the French and European industry of tomorrow.