Bio-informaticien (H/F) Etude Cancer Pediatrique

Gustave Roussy, Europe's leading cancer center, is recruiting a **Bioinformatician or Computational biologist **to join our group Research Unit 1015, headed by Dr. L. ZITVOGEL, as part of Florent GINHOUX's team working on the **"IMMUNE-ORGANOIDS: role of the immune system in the development of childhood and adolescent cancer" **project. **The position is for a 12-month fixed-term contract (with the possibility of a 6-month extension).** **Possibility of extension to a permanent site contract.** We will develop brain organoids from iPSC derived from children and adolescent with cancer, and measure the time-series transcriptomics, metabolomics and proteomics of tumor cells and microenvironment. Single-cell RNA-seq, ATAC-seq and spatial transcriptomics will be conducted for the generated organoids. The work is based on our publications (e.g., Takata et al., Immunity, 2017;Dong et al. Nature, in press). We are looking for someone with experience in single-cell RNA-seq data analysis, and multiomics data integration. **Basic Qualifications** - Master’s degree in bioinformatics/computational biology or a related field with 1+ year of experience, or a PhD in bioinformatics, computational biology, genomics, or a related field. - Proficient in Unix, R, and advanced knowledge in commonly-used programming language, such as Python. **Additional Qualifications and Skills** - Knowledge in Linux shell scripting, high performance computing, and workflow management systems such as Snakemake or Nextflow - Excellent written and verbal communication skills, including the ability to document methods and results clearly and concisely for tutorials and manuscripts - Ability to interact well with a broad constituency including students, postdoctoral fellows, faculty, and research staff. **Additional Information** **Department** France - This is a one-year term position with the possibility of extension based on performance - All formal written offers will be made by Gustave Roussy Human Resources. Florent Ginhoux laboratory “Myeloid cells in health and disease” INSERM Unit 1015 Gustave Roussy 114 Rue Edouard Vaillant 94805 -Villejuif **Key responsibilities include**: - Analyze data in collaboration with scientists generating sequencing data from organoids (“Immune - organoids” project) - Work closely with Gustave Roussy faculty, postdocs, and students to advise on analysis of sequencing data and other biological ‘big data.’ - A key part of this responsibility will be to incorporate pedological best practices to build a highly valued set of training material. This is a flexible job that provides opportunities for research and extensive collaboration in the context of a strong intellectual environment with good work-life balance. The Ginhoux group lies at the intersection of scientific research and large-scale computational analysis and works with many research groups. We are thus looking for someone who has a keen ability for picking up new knowledge and enjoys working on a wide variety of projects across a range of methods. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, gender identity, sexual orientation, pregnancy, or any other characteristic protected by law. **Working Conditions** - Work is performed in an office setting. - This position will be based on our laboratory in Gustave Roussy, with the possibility of having ahybrid in-person/remote schedule. We are seeking talented and passionate people to join our team. If you are interested in joining us, information for three references. **Job Type**: Contract Contract length: 12 months **Salary**: 1,600.00€ - 3,000.00€ per month Work Location: In person