Scientist Ii Bioreactor Process Design

Permanent position(CDI)
- General Summary :_

Just-Evotec Biologics is looking for Scientist II of Bioreactor Process Design to join a fast-paced, collaborative, and multidisciplinary team working on upstream process development (perfusion and intensified fed-batch) projects. In this role, you will participate in further developing and refining Just’s next-generation continuous bioprocessing platform, which we are currently running in our Seattle and Redmond manufacturing facilities at 500L and 1000L scale. Just-Evotec employees are driven by our mission: to expand access to therapeutics by substantially driving down the cost of goods through process technology development. This role is well-positioned to have a substantial impact on patients and the biotechnology industry.
- Missions and responsibilities_:
- Driving all aspects of Upstream process development, characterization, and technology transfer to cGMP manufacturing for hybrid and continuous processes.- Serving as an internal technical resource for cGMP manufacturing and Process Design.- Clearly and effectively communicating scientific information, experimental plans, and data to internal project teams, senior management, and technology development collaborators.- Independently designing, executing, and analyzing statistically designed experiments (DOE).- Authoring work instructions, reports, and slides which summarize, organize, and interpret experiment results with review by appropriate team members.- Responsible for bench-scale bioreactor operations including run preparation, bioreactor assembly, autoclave, inoculation, daily sampling and analytics, troubleshooting, cleaning, and maintenance.- Driving technology development for process intensification and continuous manufacturing to reduce manufacturing costs and footprint through improvements in culture productivity, control of product quality, and data management.- Responsible for equipment calibrations and Media preparations in the Lab.- Ensure accurate and complete documentation of lab activities and write appropriate technical reports for successful regulatory submission.- Ensure the upstream development (USP) labs and equipment is maintained under optimal working conditions and assume responsibility for specific instruments.- Contribute to investigations (e.g., deviations) as required to help identify the root cause and propose and implement appropriate corrective actions.- Author, amend and review operating documents, such as WI, SOPs, guidelines, and data records. Willing to take on additional activities.- Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.- Working with vendors and manufacturers.- Availability to work occasionally on weekends and evenings is required. (5-day work week/ 2 consecutive days off).
- Knowledge, skills and abilities_:
- Excellent attention to detail, focused when completing technical tasks.- Strong writing skills and efficient at documentation.- Excellent experimental design and analysis skills.- Able to stay organized in complex situations, keep track of multiple tasks and data- Enthusiastic problem-solver.- Experience with Microsoft Office apps (Word, PowerPoint, Excel).- Experience with cell culture operations, filtration techniques, automation, analysing data using statistical tools.
- Experience and education_:
- Master’s degree in engineering, Biochemistry, Biotechnology or related field with 7+ years of experience or PhD with 3+ years of experience in Biosimilars for mammalian derived purification process._- Proficiency in both verbal and written English is essential._
- Other information_:
- Desire to work in a fast, collaborative, and team-oriented environment