Associate Scientist Bioreactor Process Design

il y a 2 semaines


Toulouse, France Evotec Temps plein

Associate Scientist Bioreactor Process Design

CDI/Permanent contract
- General Summary :_

Just-Evotec Biologics is looking for Associate Scientist of Bioreactor Process Design to join a fast-paced, collaborative, and multidisciplinary team working on upstream process development (perfusion and intensified fed-batch) projects. In this role, you will participate in further developing and refining Just’s next-generation continuous bioprocessing platform, which we are currently running in our Seattle and Redmond manufacturing facilities at 500L and 1000L scale. Just-Evotec employees are driven by our mission: to expand access to therapeutics by substantially driving down the cost of goods through process technology development. This role is well-positioned to have a substantial impact on patients and the biotechnology industry.
- Missions and responsibilities_:

- Assisting in all Lab activities including experiment execution, Bioreactor assembly, Autoclave, Media/buffer preparation, Bioreactor sampling and daily sample analysis, Sample storage etc.
- Executing statistically designed experiments (DOE) with support from Scientist/Senior Scientists.
- Responsible for bench-scale bioreactor operations including run preparation, bioreactor assembly, autoclave, inoculation, daily sampling and analytics, troubleshooting, cleaning, and maintenance.
- Responsible for equipment calibrations and Media preparations in the Lab.
- Ensure accurate and complete documentation of lab activities and write appropriate technical reports for successful regulatory submission.
- Ensure the upstream development (USP) labs and equipment is maintained under optimal working conditions and assume responsibility for specific instruments.
- Contribute to investigations (e.g., deviations) as required to help identify the root cause and propose and implement appropriate corrective actions.
- Carry out Development/Characterisation/optimisation experiments, accurately document results, and produce experimental reports.
- Responsible for own professional attitude and for sharing knowledge for the benefit of others or on demand.
- Author, amend and review operating documents, such as WI, SOPs, guidelines, and data records. Willing to take on additional activities.
- Documenting best practices and technical results in ELNs, SOPs, summary reports, etc.
- Working with vendors and manufacturers
- Potential for weekend work (5-day work week/ 2 consecutive days off)
- Knowledge, skills and abilities_:

- Excellent attention to detail, focused when completing technical tasks.
- Strong writing skills and efficient at documentation
- Able to stay organized in complex situations, keep track of multiple tasks and data
- Enthusiastic problem-solver
- Experience with Microsoft Office apps (Word, PowerPoint, Excel)
- Experience with cell culture operations, filtration techniques, automation, analyzing data using statistical tools.
- Experience and education_:

- Bachelor degree in Engineering, Biochemistry or related field and +2 years of relevant experience
- Other information_:

- Desire to work in a fast, collaborative, and team-oriented environment



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