Lead PK/PD Modeling Specialist

il y a 21 heures

SaintMartinLacaussade, Nouvelle-Aquitaine, France Mercor Temps plein

About The Job
Mercor
connects elite creative and technical talent with leading AI research labs. Headquartered in San Francisco, our investors include
Benchmark
,
General Catalyst
,
Peter Thiel
,
Adam D'Angelo
,
Larry Summers
, and
Jack Dorsey
.

Position:
Translational/Clinical Pharmacology Decision-Maker

Type:
Contract / part-time
Compensation:
$150–$200/hour
Location:
Remote
Role Responsibilities

  • Evaluate the validity of dose–exposure predictions and detect high-risk extrapolations.
  • Design and refine micro-evaluations for PK/PD performance, including curve fits and parameter checks.
  • Encode quantitative sanity checks into model rubrics for automated evaluation.
  • Define failure conditions such as unsafe extrapolation and invalid assumptions.
  • Collaborate with subject matter experts to ensure model integrity and improve decision-making processes.
  • Work independently and asynchronously to meet deadlines while enhancing model outputs.

Qualifications
Must-Have

  • 8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies.
  • Deep hands-on experience in PK, PD, exposure–response modeling, and ideally population PK or QSP.
  • Strong portfolio in population PK/PD, exposure–response, and parameter estimation using NONMEM, Monolix, or equivalent tools.
  • Ability to interpret model results for decision-making, not just fit data.
  • Expertise in model fitting, sensitivity analysis, and identifying non-plausible parameter spaces.

Preferred

  • Experience supporting translational or clinical pharmacology leads in dose justification.
  • Familiarity with integrating nonclinical PK/PD data (2-species GLP → human FIH extrapolation).

Compensation & Legal

  • Hourly contractor, outcome-based deliverables.

Application Process (Takes 20–30 mins to complete)

  • Upload resume
  • AI interview based on your resume
  • Submit form

Resources & Support

  • For details about the interview process and platform information, please check:
  • For any help or support, reach out to:

PS: Our team reviews applications daily. Please complete your AI interview and application steps to be considered for this opportunity.
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